http://www.sciencedirect.com/science/article/pii/S0003999314001257
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Objective
The
aim of this study was to investigate short-term and long-term effects
of repetitive peripheral magnetic stimulation (rpMS) on spasticity and
motor function.
Design
monocentric randomized, double-blind, sham-controlled trial.
Setting
neurologic rehabilitation hospital
Participants
66
patients with severe hemiparesis and mild to moderate spasticity due to
a stroke or a traumatic brain injury. On average, time since injury was
26 or 37 weeks for the intervention groups with a standard deviation of
71 and 82, respectively.
Interventions
rpMS for 20 min or sham stimulation with subsequently occupational therapy for 20 min, two times a day over a 2-week period
Main
Outcome Measure(s): modified Tardieu scale and Fugl-Meyer assessment
(arm score), assessed before therapy, at the end of the 2-week treatment
period, and 2 weeks after study treatment. Additionally, the Tardieu
scale was assessed after the 1st and before the 3rd therapy session to determine any short-term effects.
Results
Spasticity
(Tardieu >0) was present in 83% of wrist flexors, 62% of elbow
flexors, 44% of elbow extensors, and 10% of wrist extensors. Compared to
the sham stimulation group the rpMS group showed short-term effects on
spasticity for wrist flexors (p=.048), and long-term effects for elbow extensors (p<.045).
Arm motor function (rpMS group: median 5 (4-27); sham group: 4 (4-9))
did not significantly change over the study period in either group,
whereas rpMS had a positive effect on sensory function.
Conclusions
Therapy
with rpMS increases sensory function in patients with severe limb
paresis. The magnetic stimulation has, however, limited effect on
spasticity and no effect on motor function.
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