Deans' stroke musings: FDA Stiffens Warning on NSAID Cardiovascular Risk

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Wednesday, July 15, 2015

FDA Stiffens Warning on NSAID Cardiovascular Risk

You'll have to discuss this with your doctor because there are various reasons to use these post-stroke.

Common Medicine Helps Repair Brain After Stroke, Study in Rats Suggests - Ibuprofen

They concluded that while observational studies support the use of NSAIDs for prevention of AD, a randomized controlled trial (RCT) did not.

High-Dose NSAIDs Hike Risk of Heart Attack and Stroke

http://www.medpagetoday.com/PublicHealthPolicy/FDAGeneral/52530?xid=nl_mpt_DHE_2015-07-10&eun=g424561d0r
The FDA is strengthening an earlier warning about the cardiovascular safety of non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs), both prescription and nonprescription, the agency said Thursday.
After a comprehensive review of new safety information, the FDA is requiring updates to the labels of all prescription NSAIDs to reflect recent information on risk of heart attack and stroke. Over-the-counter non-aspirin NSAIDs already contain some safety information, but the labels on these drugs will also require an update, said the FDA in its announcement posted online.
The new labels for prescription NSAIDs should contain the following information, according to the FDA:

The risk of heart attack can occur within weeks of starting an NSAID, and that risk may increase with longer use.
The risk seems to be higher at higher doses.
It’s not clear if the risk of heart attack and stroke is the same for all NSAIDs.
The drugs can raise the risk of heart attack or stroke in both patients with a risk of heart disease and patients without.
Patients with heart disease or risk factors for it are at a greater risk of heart attack or stroke following the use of NSAIDs, because they have a higher risk at baseline.
There is also an increased risk of heart failure for patients using NSAIDs.