Deans' stroke musings: Coffee consumption and risk of cardiovascular events in hypertensive patients: Results from the HARVEST

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Monday, April 11, 2016

Coffee consumption and risk of cardiovascular events in hypertensive patients: Results from the HARVEST

Now that my hypertension is under control I should be able to safely benefit from coffee consumption.
http://www.mdlinx.com/internal-medicine/medical-news-article/2016/03/25/coffee-caffeine-cardiovascular-events-hypertension/6593527/?news_id=387&newsdt=040216&subspec_id=4&utm_source=WeeklyNL&utm_medium=newsletter&utm_content=Weeks-Best-Article&utm_campaign=article-section&category=latest-weekly

Paolo Palatini

¹^,

Claudio Fania¹

Susanna Cozzio¹

¹This author takes responsibility for all aspects of the reliability and freedom from bias of the data presented and their discussed interpretation.

DOI: http://dx.doi.org/10.1016/j.ijcard.2016.03.006

Article Info

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Abstract

Background

Controversy still exists about the long-term cardiovascular effects of coffee consumption in hypertension.

Methods

The predictive capacity of coffee use for cardiovascular events (CVEs) was investigated in 1204 participants from the HARVEST, a prospective cohort study of non-diabetic subjects aged 18–45 years, screened for stage 1 hypertension. Subjects were grouped into three categories of coffee drinking, non-drinkers (none), moderate drinkers (1 to 3 cups/day) and heavy drinkers (4 or more cups/day). Multivariate Cox proportional hazards models were developed adjusting for possible confounding variables and risk factors.

Results

During a median follow-up of 12.6 years, CVEs were developed by 60 participants. CVEs were more common among coffee drinkers than abstainers (abstainers, 2.2%; moderate drinkers, 7.0%; heavy drinkers, 14.0%; p for trend = 0.0003). In a multivariable Cox regression model, coffee use was a significant predictor of CVE in both coffee categories, with a hazard ratio of 2.8 (95% CI, 1.0–7.9) in moderate coffee drinkers and of 4.5 (1.4–14.2) in heavy drinkers compared to abstainers. After inclusion of change in body weight (p = ns), incident hypertension (p = 0.027) and presence of diabetes/prediabetes (p = ns) at follow-up end, the association with CVE was attenuated but remained significant in heavy coffee drinkers (HR, 95% CI, 3.4, 1.04–11.3).

Conclusions

These data show that coffee consumption increases the risk of CVE in a linear fashion in hypertension. This association may be explained in part by the association between coffee and development of hypertension. Hypertensive patients should be discouraged from drinking coffee.