http://www.mdlinx.com/internal-medicine/medical-news-article/2016/06/13/statin/6704352/?
Current Opinion in Cardiology, 06/13/2016
The
purpose of this study is to conclude the definition of statin–related
muscle disorders, causative factors, and recommended management
strategies. Statin–related muscle adverse–effects are common. Secondary
causes of muscle disease unmasked by statin therapy should be
identified. Most patients can be managed by adjustment of standard
treatment protocols.
- A number of consensus groups have defined and classified statin–related muscle disorders, whereas others have suggested diagnostic and management strategies. Mechanisms behind statin–related muscle toxicity have been identified.
- Therapeutic and clinical investigation pathways have been reviewed and algorithms defined.
- Novel drugs have become available to reduce low–density lipoprotein cholesterol levels that are not associated with causing muscle side–effects.
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