For your discussion with your doctor. Ask her/him about the 81mg vs. 300 mg in Britain and 325 mg (or 5 grains) in the United States and if the size made any difference.
http://www.alphagalileo.org/ViewItem.aspx?ItemId=170515&CultureCode=en
Stomach bleeds caused by aspirin are considerably less serious than
the spontaneous bleeds that can occur in people not taking the drug,
concludes a study led by Cardiff University.
Published in the journal Public Library of Science, the extensive
study of literature on aspirin reveals that while regular use of the
drug increases the risk of stomach bleeds by about a half, there is no
valid evidence that any of these bleeds are fatal.
Professor Peter Elwood from Cardiff University’s School of Medicine
said: “Although many people use aspirin daily to reduce the risk of
health problems such as cancer and heart disease, the wider use of the
drug is severely limited because of the side effect of bleeding from the
stomach. With our study showing that there is no increased risk of
death from stomach bleeding in people who take regular aspirin, we hope
there will be better confidence in the drug and wider use of it by older
people, leading to important reductions in deaths and disablement from
heart disease and cancer across the community.”
Heart disease and cancer are the leading causes of death and
disability across the world, and research has shown that a small daily
dose of aspirin can reduce the occurrence of both diseases by around
20-30%.
Recent research has also shown that low-doses of aspirin given to
patients with cancer, alongside chemotherapy and/or radiotherapy, is an
effective additional treatment, reducing the deaths of patients with
bowel, and possibly other cancers, by a further 15%.
The study ‘Systematic review and meta-analysis of randomised trials
to ascertain fatal gastrointestinal bleeding events attributable to
preventive low-dose aspirin: No evidence of increased risk’ can be found
in Public Library of Science.
This study was a systematic review and meta-analysis of randomised
trials. This type of research provides the strongest evidence for
drawing causal conclusions because it draws together all of the best
evidence.
Full bibliographic informationSystematic
Review and Meta-Analysis of Randomised Trials to Ascertain Fatal
Gastrointestinal Bleeding Events Attributable to Preventive Low-Dose
Aspirin: No Evidence of Increased Risk
Peter C. Elwood , Gareth
Morgan , Julieta Galante , John W. K. Chia , Sunil Dolwani , J. Michael
Graziano , Mark Kelson , Angel Lanas , Marcus Longley , Ceri J. Phillips
, Janet Pickering , Stephen E. Roberts , Swee S. Soon , [ ... ], Alison
L. Weightman
Published: November 15, 2016
http://dx.doi.org/10.1371/journal.pone.016616
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