Deans' stroke musings: DAWN of a new day for stroke patients as study promises new options and a wider treatment window

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Tuesday, August 1, 2017

DAWN of a new day for stroke patients as study promises new options and a wider treatment window

Still nothing on stopping the neuronal cascade of death by these 5 causes in the first week. No one thinks outside the bun. No mention of how many fully recovered or what disabilities still occurred.
https://scienmag.com/dawn-of-a-new-day-for-stroke-patients-as-study-promises-new-options-and-a-wider-treatment-window/
Colorado Springs–Results of the first study showing some acute stroke patients could benefit from neuroendovascular surgery 6 to 24 hours after a stroke will be presented at the Society of NeuroInterventional Surgery's (SNIS) 14th Annual Meeting.
The study could offer hope to patients who miss the 6-hour treatment window and allow doctors to offer more patients life-saving neuroendovascular surgery. No randomized trial has previously demonstrated the effectiveness of mechanical thrombectomy for acute stroke caused by a large vessel occlusion (LVO) performed more than 6 hours after the onset of a stroke.
"The results of this trial offer tremendous promise of reduced disability to patients who can still be treated after the 6-hour window and for whom until now there were no other evidence based treatment options," said co-principal investigator Dr. Tudor Jovin, from the University of Pittsburgh Medical Center.
The study, DAWN in full daylight (DWI or CTP Assessment with Clinical Mismatch in the Triage of Wake Up and Late Presenting Strokes Undergoing Neurointervention, compared patient outcome 90 days after a thrombectomy using the Trevo® Retriever and medical management or after medical management alone.

Patients were considered for the trial if they had a stroke that began within 6 to 24 hours, or had an unknown time of onset (such as stroke discovered upon waking). Researchers also considered a patient's age, the severity of their stroke symptoms and whether the patients had a clinical core mismatch: a small area of damaged brain tissue but a larger area threatened but still alive.
The trial included 206 patients before enrollment was stopped at the recommendation of the Data Safety Monitoring Board after the study passed pre-specified probability thresholds for predicted success.
The full results of the trial will be provided at the SNIS presentation. The study's principal investigator is Raul Nogueira, MD.
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About the Society of NeuroInterventional Surgery
The Society of NeuroInterventional Surgery (SNIS) is a scientific and educational association dedicated to advancing the specialty of neurointerventional surgery through research, standard-setting and education and advocacy in order to provide the highest quality of patient care in diagnosing and treating diseases of the brain, spine, head and neck. http://www.snisonline.org. Follow us on Twitter @SNISinfo.
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