Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Monday, October 16, 2017

Magic Mushrooms “Reset” Key Brain Circuits in Depressed People

Well, nothing has come of these earlier reports on magic mushrooms. If we can't even legalize marijuana mushrooms will never get there either. Don't do this, there is NO proof it works or any amount or purity available.

Eat more mushrooms if you want to avoid dementia  Jan. 2017 

Edible and medicinal mushrooms show potential to mitigate neurodegenerative diseases  Feb. 2017 

How Magic Mushrooms Affect Your Brain: From Higher Levels Of Awareness To Hallucinations   March 2015

The latest here:

Magic Mushrooms “Reset” Key Brain Circuits in Depressed People

Psychedelics like lysergic acid diethylamide (LSD) and psilocybin are popular for their use as party drugs, but less so for what researchers claim to be their therapeutic effects — which has been a major focus for a number of clinical trials in the last decade. Magic mushrooms, for example, have been the focus of some recent work that saw how it could help with treating some of the symptoms of clinical depression. For instance, a study from the U.S. last year showed how a single does of psilocybin can lift anxiety and depression felt by cancer patients.
Now, scientists from the Imperial College London have found how psilocybin, which is the active psychedelic compound that occurs naturally in magic mushrooms, can “reset” brain activity in patients suffering from depression. Their study, which was published in the journal Scientific Reports on Friday, highlights how psilocybin gave patients a “kick start” in fighting clinical depression.


psychadelics magic mushrooms psilocybin mental health
Image credit: Robin Carhart-Harris/Imperial College London
The researchers at Imperial gave two doses (10 mg and 25 mg) of psilocybin, with a week in between each dose, to 20 patients with a treatment-resistant form of depression. Immediately after receiving the doses, the patients said they felt a decrease in depressive symptoms, which MRI scans of their brains revealed to have been due to a reduce in blood flow to areas involved in handling emotional responses, stress, and fear.

Rebooting Through Depression with Magic Mushrooms

In short, the patients experienced a sort of reboot. “We have shown for the first time clear changes in brain activity in depressed people treated with psilocybin after failing to respond to conventional treatments,” Robin Carhart-Harris, head of Psychedelic Research — there’s such a thing — at Imperial, said in a press release. “Several of our patients described feeling ‘reset’ after the treatment and often used computer analogies. For example, one said he felt like his brain had been ‘defragged’ like a computer hard drive, and another said he felt ‘rebooted’.”



It would seem that during the drug “trip,” brain networks went through an initial disintegration that was followed by a re-integration afterwards, when the patients “come down” from the psychedelic. “Psilocybin may be giving these individuals the temporary ‘kick start’ they need to break out of their depressive states and these imaging results do tentatively support a ‘reset’ analogy. Similar brain effects to these have been seen with electroconvulsive therapy,” Carhart-Harris added.
The researchers acknowledged, however, that while their study provides a new window into the brains of people who’ve taken psychedelics, the small number of patients tested and the absence of a control/placebo group limits the significance of their study. “Larger studies are needed to see if this positive effect can be reproduced in more patients,” said senior author David Nutt, director of the Neuropsychopharmacology unit of the Brain Sciences division at Imperial. “But these initial findings are exciting and provide another treatment avenue to explore.” The researchers also warned against self-medicating using such psychedelics.

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