Oooh, big words galore. No clue on meaning.
Immediate Plasticity of Parietal-Frontocentral Functional Connections in Music-Reality based Post-Stroke Rehabilitation
Publisher: IEEE
Abstract:
Post-stroke
neuronal plasticity was always viewed as a localized
gain-of-functionality. The reorganization of neurons neighboring the
lesioned brain tissues is able to compensate for the function of damaged
neurons. However, it was also proposed that distant interconnected
brain regions could be affected by stroke. Changes in functional
connections across the brain were found associated with motor deficiency
and recovery. Parietal-frontocentral functional connectivity was found
related to the performance of motor imagery. This study aims to evaluate
the EEG-based parietal-frontocentral functional connectivity in
post-stroke patients, and to investigate the immediate effect of
rehabilitation training toward these connections. Pairwise functional
connectivity was extracted from healthy subjects and post-stroke
patients during standing and walking. Significant reductions in P3-FC4
and P3-C4 connectivity strengths were found in post-stroke patients
during both standing and walking conditions. Immediate improvement in
the reduced connections was observed with the intervention of a
previously proposed, motivation-based rehabilitation system, which was
known as the mixed-reality music rehabilitation (MR
2
) system. This indicates the relationship between left parietal
functional connectivity and stroke-related motor performance. These
findings suggest the feasibility to evaluate the immediate plasticity of
functional connectivity during post-stroke rehabilitation.
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