Deans' stroke musings: Neurons that allow stroke victims to walk again have been identified

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Friday, November 11, 2022

Neurons that allow stroke victims to walk again have been identified

Nothing here is for stroke.

Neurons that allow stroke victims to walk again have been identified

His exploits make him the talk of the town Since few months : Thanks to a revolutionary method, a Swiss laboratory, NeuroRestore, makes partially or completely paralyzed people walk again! In an article published Wednesday in the journal Nature, the team co-directed by its two directors has already demonstrated the results of this clinical trial in nine patients. And heralds a decisive step: the precise identification of the neurons that allow you to sit on your own two feet and move forward is the promise of good news for those suffering from this form of disability.

Nine patients with chronic spinal cord injury were treated with electrical stimulation to regain the ability to walk. All patients showed improved mobility after five months of rehabilitation. But for researchers, the mechanism behind this achievement is unclear. As changes in neural activity during the treatment elicited awareness, French neuroscientist Grégoire Courtin, Swiss neurosurgeon Jocelyn Bloch and their team investigated whether specific neurons were involved in the return to walking. To do this, they had to use a mouse spinal cord model.

3D Mapping

The researchers thus created a 3D map of the spinal cord, which enabled them to observe the recovery process at the cellular level. This revealed the surprising property of a family of neurons expressing the gene VSX2. Although these cells may not be useful for the entire possession of the rat, on the other hand they may allow the recovery of motor function after spinal cord injury.

Thanks to the implants, the researchers stimulated the rodents’ spinal cords by deactivating the neurons in question. Injured mice immediately stopped walking, while this dysfunction had no effect on intact rodents, showing that this family of neurons is essential for repair. Their manipulation will be enough to regenerate the spinal cord, scientists want to believe. However, other neurons in the brain and spinal cord contribute to gait recovery, the study authors say. Hence further studies are required.