Is your competent? doctor testing for this? AND HAS EXACT PROTOCOLS TO REDUCE IT? NO? So, you DON'T have a functioning stroke doctor, do you? RUN AWAY!
In here is something your incompetent doctor should have had you doing years ago! In my opinion incompetent is the correct word, doctors should be up-to-date on all research in their specialty. 7 years is way too long to be incompetent and still employed as a doctor!
Study: Tree nut consumption linked to improved type 2 diabetes health May 2018
The latest here:
Blood Fat Links Found Between Heart Risk and Alzheimer’s
Summary: New research reveals complex relationships between blood lipid levels and the risk of developing Alzheimer’s disease, the most common form of dementia. While small dense LDL cholesterol—linked to heart disease—was associated with increased Alzheimer’s risk, other markers like ApoB48 were linked to reduced risk.
Surprisingly, even low levels of “good” HDL cholesterol were associated with lower dementia risk in this study. These findings suggest that lipid metabolism may play different roles in heart and brain health, and that blood lipid profiles could help predict or even prevent Alzheimer’s.
Key Facts:
- Bad Cholesterol Link: Higher small dense LDL-C levels were tied to a 21% increased Alzheimer’s risk.
- Protective Fat Marker: Higher ApoB48 levels—linked to dietary fat transport—were tied to a 22% lower risk.
- Unexpected HDL Finding: Participants with the lowest HDL-C (good cholesterol) had a 44% lower Alzheimer’s risk.
Source: UT Southwestern
People who are at higher risk for heart disease also seem more likely to develop dementia.
And
research led by The University of Texas Health Science Center at San
Antonio (UT Health San Antonio) has discovered new associations between
various lipid, or fat, levels in the blood and the risk of developing
Alzheimer’s disease, the most common cause of dementia worldwide.
The
findings mean that using blood lipid profiles could help better
understand, predict and possibly even prevent the disease in the future.
In
more than 800 older adults who were part of the long-running Framingham
Heart Study, the researchers found that higher levels of small dense
cholesterol particles – which are known to increase the risk of
atherosclerosis and coronary heart disease – were associated with higher
risk of developing Alzheimer’s disease.
However, higher levels
of a marker for small fat-carrying particles, which are involved in the
transport of dietary fats from the gut to other body tissues through the
blood after eating, were associated with lower risk of developing the
disease.
Perhaps ironically, the researchers also discovered that
individuals who had the lowest levels of highly dense cholesterol
particles – often referred to as “good cholesterol” as it is considered
protective against cardiovascular disease – had a lower risk of
developing Alzheimer’s disease compared to the rest of the included
individuals.
“These findings highlight the complex relationships
of blood lipids with both heart and brain health, suggesting the
possibility of certain blood lipids playing different roles in
cardiovascular disease and dementia-related biological processes,” said
Sokratis Charisis, MD, a researcher with the Glenn Biggs Institute for
Alzheimer’s and Neurodegenerative Diseases at UT Health San Antonio.
Charisis is first author of the study published May 30 in the journal Neurology,
titled, “Association of Blood Lipoprotein Levels With Incident
Alzheimer’s Disease in Community-Dwelling Individuals: The Framingham
Heart Study.” Other authors include corresponding author Sudha Seshadri,
MD, director of the Biggs Institute, and researchers from Boston
University School of Public Health, the University of Texas Rio Grande
Valley and the Framingham Heart Study.
A community-based analysis
The
new study notes that dementia is a leading source of morbidity and
mortality in the aging population. Worldwide, there were 57.4 million
people living with dementia in 2019, a number that is expected to reach
152.8 million by 2050.
However, there is a general trend over
time of decreasing incidence of Alzheimer’s disease and other dementias
in the U.S. and other higher-income countries that is at least partially
attributed to better management of cardiovascular risk factors.
The
Framingham Heart Study is an ongoing, community-based cohort study that
was launched in 1948 in Framingham, Massachusetts. Residents there ages
30 to 59 were randomly selected from census data to participate. Those
with definite signs of cardiovascular disease at baseline were excluded.
Participants of the original cohort have undergone up to 32
examinations performed every two years, which have included detailed
history-taking by a physician, a physical examination and lab testing.
The
latest analysis by researchers led by UT Health San Antonio included
participants from the original cohort who were 60 years or older and
free of dementia during an examination period of 1985-1988, and had
available cognitive follow-up and lipoprotein marker data. Lipoproteins
act as a transport system for lipids in the bloodstream.
Blood lipid levels and dementia
Levels of high-density lipoprotein cholesterol (HDL-C), or good cholesterol; low-density lipoprotein cholesterol (LDL-C), or “bad cholesterol”; small dense LDL-C (sdLDL-C); and other lipoprotein types associated with heart disease were measured in blood samples obtained from the mid- to late-‘80s examination period.
The Framingham participants were watched for incident Alzheimer’s disease, meaning a first diagnosis of the disease, until 2020.
Of a total of 822 participants, 128 developed incident Alzheimer’s disease.
The
researchers discovered that an increase of 1 standard deviation unit
(SDU) of a concentration of small dense LDL-C (sdLDL-C), a value
representing how far a specific data point deviates from the mean, was
associated with a 21% increase in the risk for incident Alzheimer’s
disease.
As the name implies, small dense LDL-C (sdLDL-C) is a
type of the so-called bad cholesterol with smaller and denser particles
than other low-density lipoproteins, and that is considered more likely
to form plaque in arteries, strongly associated with an increased risk
of atherosclerotic cardiovascular disease.
A 1 SDU increase in a
concentration of ApoB48, a lipoprotein that transports dietary fat from
the intestines and into the bloodstream that also is tied to heart
disease and cardiovascular problems, was found to be associated with a
22% decrease in the risk for incident Alzheimer’s disease.
Participants
in the first quartile of HDL-C, or good cholesterol – in order of
lesser amounts – were 44% less likely to develop Alzheimer’s compared
with those in the second, third and fourth quartiles. And those with
small dense LDL-C concentrations below the median were 38% less likely
to develop Alzheimer’s compared with those with concentrations above the
median.
In summary, then, lower small-density bad cholesterol
(sdLDL-C) concentrations and higher ApoB48 concentrations were
associated with a lower Alzheimer’s risk. And individuals with the
lowest good cholesterol (HDL-C) concentrations were less likely to
develop Alzheimer’s compared with the remaining sample.
“These
findings underscore links between lipoprotein metabolism pathways and
Alzheimer’s risk, emphasizing the potential role of blood lipoprotein
markers in Alzheimer’s risk stratification and of lipid modification
strategies in dementia prevention,” the researchers concluded.
About this cholesterol, cardiovascular disease, and dementia research news
Author: Steven Lee
Source: UT Southwestern
Contact: Steven Lee – UT Southwestern
Image: The image is credited to Neuroscience News
Original Research: Closed access.
“Association
of Blood Lipoprotein Levels With Incident Alzheimer’s Disease in
Community-Dwelling Individuals: The Framingham Heart Study” by Sokratis Charisis et al. Neurology
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