Deans' stroke musings: Suppressing Immunosuppression after Stroke

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Sunday, December 4, 2011

Suppressing Immunosuppression after Stroke

I wish they had chosen a more understandable title.

Suppressing Immunosuppression after Stroke

This article has no abstract; the first 100 words appear below.

Pneumonia is a major cause of death after acute cerebral ischemia. A recent study by Wong and colleagues¹ provides some insight into susceptibility to infection after stroke. Specifically, they found that infections after stroke are promoted by noradrenergic-mediated dysfunction of a small subset of lymphocytes — the invariant natural killer T cells.

More than 40% of patients die within a few weeks after stroke or have severe long-term disabilities. Although two thirds of these outcomes are attributed to nonmodifiable factors, such as the severity of the initial stroke and the patient's age, the remaining third is consequent to modifiable factors . . .

Disclosure forms provided by the authors are available with the full text of this article at NEJM.org.