Deans' stroke musings: Presentations from the just completed Neuroscience 2011

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Wednesday, December 14, 2011

Presentations from the just completed Neuroscience 2011

Studies highlight the brains resiliency to damage
Presentations from the just completed Neuroscience 2011 show some fascinating possibilities for stroke recovery. None of these will help us directly but for future strokees, if enough research is done there may be some hyperacute therapies.
Previous studies, led by Ron Frostig, PhD, of the University of California, Irvine, found that anesthetized rats undergoing an ischemic stroke could be protected from brain damage if they received sensory stimulation within two hours of stroke onset. The current study found rats were also fully protected if immediately awakened from anesthesia after ischemic stroke and placed in an “enriched environment” replete with buried treats, tunnels, and toys.
http://www.sfn.org/siteobjects/published/0000BDF20016F63800FD712C30FA42DD/7EEDCCFAE51E16A50C47ADCDB808E614/file/Brain%20Repair%20Release%20Final%20Draft.pdf
This does contradict what Jill Bolte-Taylor did to recover from her stroke, she went into shutdown mode with overstimulation.

This one is weird, it seems to say that small blood clots in capillaries can be enveloped and pushed out thru the walls. Great picture at the link.
http://www.ncbi.nlm.nih.gov/pubmed/20505729
The picture shows pericytes which are suspected of not opening up the small capillaries even after the main arteries are cleared via tPA. This becomes one of the problems in the neuronal cascade of death.
Pericytes talked about here:
Even after a clot is gone, about half of capillaries remain constricted—at least in mice—even though blood flow is restored in larger vessels. Researchers have found that free radicals in blood vessels lead to this constriction.
http://www.dana.org/news/brainwork/detail.aspx?id=23436