Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Wednesday, July 31, 2024

Script generation a reliable tool to determine early cognitive impairment in older adults

Will your competent? doctor use this to set a baseline for your cognitive ability post stroke? NO? So you don't have a functioning stroke doctor then, do you? My Mom at 95 had a sequencing test of brewing coffee in a coffepot to get her out of rehab and home. She required a lot of suggestions since she only does that when I'm around, maybe 10-15 times a year. So that was an invalid test for her. You'll have to make sure this script test is actually valid.

Your chances of getting dementia. YOUR DOCTOR IS RESPONSIBLE FOR PREVENTING THIS!

1. A documented 33% dementia chance post-stroke from an Australian study?   May 2012.

2. Then this study came out and seems to have a range from 17-66%. December 2013.`    

3. A 20% chance in this research.   July 2013.

4. Dementia Risk Doubled in Patients Following Stroke September 2018 

The latest here:

Script generation a reliable tool to determine early cognitive impairment in older adults 

Key takeaways:

  • Healthy controls performed better in testing for everyday tasks than those with mild cognitive impairment.
  • Those with MCI performed poorer than healthy counterparts in episodic memory and executive function.

PHILADELPHIA — Script generation task performance may be a cost-effective, reliable tool to assess early cognitive impairment in older adults, according to a poster presentation.

“We’re looking for a more accessible screening tool for early detection of cognitive changes, so we’re looking at script generation as an inexpensive way,” Melissa Rosahl, BA, a pending neuropsychology graduate student at Temple University, told Healio at the Alzheimer’s Association International Conference.

Aptinyx’s NYX-458 was not efficacious in a phase 2 trial in patients with Parkinson’s disease and Lewy body dementia. Image: Adobe Stock
According to new research, script generation may be a reliable tool to assess early cognitive issues in older adults from underserved communities. Image: Adobe Stock

Rosahl and colleagues from Temple sought to examine whether script generation — which requires an individual to verbalize instructions for certain everyday tasks such as house work — could accurately detect signs of cognitive decline in older adults in underserved communities.

Their study included 74 individuals from the area adjacent to Temple University, 51 deemed of healthy cognition (mean age 72.8±5.3 years; 69% female) and 23 with mild cognitive impairment (MCI; mean age 75.8±8.7 years; 61% female) who completed a series of script-generation tasks in the kitchen such as completing all steps necessary in making toast, coffee and a sandwich along with a separate battery of cognitive tests. All participants additionally submitted to the Naturalistic Action Task (NAT), a standardized test of functioning, for the same kitchen-based duties.

The primary outcome for the study was script generation ability in healthy controls compared with the same ability in those in the MCI group. The secondary outcomes included a comparison of script generation performance in all participants against executive function and episodic memory, as well as script generation performance compared with NAT performance.

Results showed a significant difference in script generation task performance between healthy participants and their counterparts diagnosed with MCI, with respect to the average number of total essential and non-essential steps completed, the total time elapsed to complete the script, the number of verbalized words total number of scripted errors.

Those in the MCI group additionally performed poorer in episodic memory and executive function compared with healthy counterparts, as well as on the NAT version of the kitchen tasks with respect to the number of steps, total time and number of errors.

“They completed significantly fewer essential steps to the task,” Rosahl explained. “They were omitting essential steps and also non-essential task-related steps.”

Sources/Disclosures

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Source:

Rosahl M, et al. Relations between language production and everyday functioning in older adults. Presented at: Alzheimer’s Association International Conference; July 28-Aug. 1, 2024; Philadelphia.

Disclosures: Rosahl reports no relevant financial disclosures

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