Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Friday, May 16, 2025

Depression after stroke can seriously affect health for a decade, new research shows

 Post stroke depression is best prevented by EXACT 100% RECOVERY PROTOCOLS! Since the stroke medical world has completely failed at that task, they should all be fired for extreme incompetence and never allowed near anything medical again!

Depression after stroke can seriously affect health for a decade, new research shows

People who experience depression following a stroke may face a higher risk of poor health and even death for up to a decade afterward, new research finds.

A study by researchers from King's College London has found that post-stroke (PSD) can have serious on stroke survivors, lasting up to 10 years after the initial stroke. The findings emphasize a need for long-term mental health support in stroke rehabilitation.

Researchers tracked more than 2,500 stroke survivors using data from the South London Stroke Register, a population-based register recruiting living within Lambeth and Southwark. They examined the participants' health for up to 10 years to understand the long-term consequences of depression for stroke survivors.

Published in The Lancet Regional Health—Europe, the study found that 36% of participants showed signs of depression three months after their stroke and survivors with PSD were nearly three times more likely to develop long-term physical disability compared to those without depression. They also faced a 30% higher risk of death in the decade following their stroke and were more likely to struggle with daily tasks and have a reduced quality of life.

Continued depression at one or five years after the stroke was associated with higher risks of death, more physical disability and lower quality of life. In contrast, survivors who recovered from PSD within the first year had a similar risk of death to those who never experienced depression.

Recovery during this period was also linked to a lower risk of another stroke, better functional outcomes, and improved quality of life. Although the timing of depression onset didn't appear to affect long-term health risks, recovering from depression was associated with better physical and mental well-being.

Mortality up to 10-years after stroke by depression status at 3-months. Credit: The Lancet Regional Health - Europe (2025). DOI: 10.1016/j.lanepe.2025.101324

Lu Liu, a Ph.D. student at King's College London and lead researcher on the study, said, "Post-stroke depression is linked to higher mortality and worse functional outcomes, but most previous studies have only followed patients for less than a year. Our study examined the long-term impact of depression after a stroke. These findings show how important it is to recognize and treat depression as part of stroke recovery."

Depression was identified using a questionnaire, and participants' ability to perform daily activities, their physical independence, and their overall quality of life, both physical and mental, were also assessed.

The South London Stroke Register has been collecting data since 1995, but follow-up typically ends after 10 years, as tracking patients beyond this point becomes increasingly difficult due to cognitive decline or communication challenges, which can affect the reliability of the data.

Professor Yanzhong Wang, Professor of Statistics in Population Health at King's College London and co-senior author of the study, added, "People often take depression seriously in the first few months after a stroke, but years later it can be overlooked. Just because the stroke happened five or six years ago doesn't mean the depression is any less serious.

"Our findings show that post-stroke depression remains a major risk factor long after the initial stroke and needs ongoing attention from clinicians."

Dr. Matthew O'Connell, Senior Lecturer in Health Services Research and Population Health Sciences at King's College London and co-senior author of the study, said, "The South London Stroke Register is unique in following for so many years after their stroke. Encouragingly, our data show those recovering from depression experience better outcomes in the longer term, suggesting effectively treating these symptoms could have broader-ranging health benefits."

Currently, post-stroke care primarily focuses on physical recovery, with depression often only screened in the early stages. The researchers hope their findings will encourage the inclusion of long-term mental health support in stroke rehabilitation programs. While more research is needed to develop effective treatments for PSD, these results underline the need for continued care that addresses both physical and mental health.

More information: Lu Liu et al, Long-term outcomes of depression up to 10-years after stroke in the South London Stroke Register: a population-based study, The Lancet Regional Health - Europe (2025). DOI: 10.1016/j.lanepe.2025.101324

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