Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Saturday, February 18, 2012

Cool Aid: Drug That Lets Body Temperature Drop Could Save Stroke Victims

This might be easier than the cooling helmet or cooling pads that need skin contact.
http://www.scientificamerican.com/article.cfm?id=cool-aid-drug-that-causes&WT.mc_id=SA_syn_HuffPo

During the last decade, a series of studies in The New England Journal of Medicine chronicled the potential benefits of rescuing patients from stroke, heart attack and other conditions by lowering body temperature to reduce demand for oxygen. Depressed body temperature may also have manifold effects beyond the ones described—anything from prolonging life span to inducing a lower metabolic state suitable for long-distance spaceflight.

A hurdle to lowering body temperature to protect brain cells after stroke is the body's own cold-defense mechanisms. Unless a patient is anesthetized, blood vessels in the skin constrict, shivering begins, brown fat generates heat and a patient experiences the natural urge to seek a warmer environment. All of these "thermo-effector responses" are there to keep things steady at 37 degrees Celsius (98.6 degrees Fahrenheit).

An experimental drug demonstrated by researchers at the Fever Lab in Saint Joseph's Hospital and Medical Center in Phoenix and their collaborators points to a way around the thermo-effector blockade. The agent blocked a receptor on nerve cells in mice and rats called TRPM8 that is normally activated by skin cooling to set in motion the body’s cold-defense armamentarium. The drug, a compound called M8-B, stopped even moderately chilled animals from mounting a cold response, thereby lowering core body temperature. "The body stops defending its temperature," says Andrej Romanovsky, who heads the Fever Lab.

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