http://journal.frontiersin.org/article/10.3389/fneur.2016.00152/full?
- 1Neurology and Neurorehabilitation Center, Luzerner Kantonsspital, Luzern, Switzerland
- 2Gerontechnology and Rehabilitation Group, University of Bern, Bern, Switzerland
- 3Wissenschaftliches Institut, Klinik Bavaria in Kreischa GmbH, Kreischa, Germany
- 4ARTORG Center for Biomedical Engineering Research, University of Bern, Bern, Switzerland
Background: Good responsive functional outcome
measures are important to measure change in stroke patients. The aim of
study was to compare the internal and external responsiveness, floor and
ceiling effects of the motor, cognition, and communication subscales of
the Lucerne ICF-based Multidisciplinary Observation Scale (LIMOS) with
the motor and cognition subscales of the Functional Independence Measure
(FIM), and the Barthel Index (BI), in a large cohort of stroke
patients.
Methods: One hundred eighteen stroke patients
participated in this study. Admission and discharge score distributions
of the LIMOS motor, LIMOS cognition and communication, FIM motor and FIM
cognition, and BI were analyzed based on skewness and kurtosis. Floor
and ceiling effects of the scales were determined. Internal
responsiveness was assessed with t-tests, effect sizes (ESs), and
standardized response means (SRMs). External responsiveness was
investigated with linear regression analyses.
Results: The LIMOS motor and LIMOS cognition and
communication subscales were more responsive, expressed by higher ESs
(ES = 0.65, SRM = 1.17 and ES = 0.52, SRM = 1.17, respectively) as
compared with FIM motor (ES = 0.54, SRM = 0.96) and FIM cognition (ES =
0.41, SRM = 0.88) and the BI (ES = 0.41, SRM = 0.65). The LIMOS
subscales showed neither floor nor ceiling effects at admission and
discharge (all <15%). In contrast, ceiling effects were found for the
FIM motor (16%), FIM cognition (15%) at discharge and the BI at
admission (22%) and discharge (43%). LIMOS motor and LIMOS cognition and
communication subscales significantly correlated (p < 0.0001) with a change in the FIM motor and FIM cognition subscales, suggesting good external responsiveness.
Conclusion: We found that the LIMOS motor and
LIMOS cognition and communication, which are ICF-based multidisciplinary
standardized observation scales, might have the potential to better
detect changes in functional outcome of stroke patients, compared with
the FIM motor and FIM cognition and the BI.
Introduction
Several measures for activities of daily living (ADL)
have been published for patients with stroke. Among those, the Barthel
index (BI) (1) and the functional independence measure (FIM) (2) are most widely used (3–5).
The FIM covers two main aspects of functional outcome, by including a
motor and cognitive subscale, while the BI includes motor items only.
Previous studies have explored floor and ceiling effects, and
responsiveness of both FIM subscales, often comparing the FIM motor
subscale with the BI. No clear advantage of the FIM motor subscale over
the BI has been found (6, 7). In addition, floor and ceiling effects have been suggested for both FIM motor subscale (7–9) and BI (10, 11).
An attempt to overcome ceiling effects and to extend the range of the
FIM has been the adding of 12 additional items of the functional
assessment measure (FAM) to the FIM, so-called FIM + FAM (12). However, the added value of the FAM can be questioned, since ceiling effects still remained (12, 13).
Consequently, the FIM is still most commonly used as a reference
functional outcome measurement and this, in particular, in stroke
rehabilitation centers (5).
Recently, the Lucerne ICF-based Multidisciplinary Observation Scale (LIMOS) has been developed (14).
In this study, it was found that the scale covers four components,
which can be defined as LIMOS motor, LIMOS cognition, LIMOS
communication, and LIMOS domestic life subscales. These LIMOS subscales
have several advantages. First, the composition and rating of the scales
are based on the International Classification of Functioning,
Disability, and Health (ICF) (15–18). In fact, the selection of the items of the LIMOS is based on the comprehensive ICF core sets for stroke (17).
Second, the scales are used by a multidisciplinary team (nurses,
physical and occupational therapists, speech therapists, neurologists).
Finally, with respect to the LIMOS motor and LIMOS cognition, for
example, these include detailed motor items, such as carrying objects
(d430), and cognitive items, such as focusing attention (d160).
Therefore, the more comprehensive LIMOS subscales are expected to be
more sensitive to change over time than the other measures.
The test–retest, inter-rater reliability and construct
validity of the total LIMOS and its subscales has been previously
confirmed (14).
However, the internal and external responsiveness, which are important
psychometric properties, still remains to be established. The internal
responsiveness is defined as the ability of a measure to change over a
specific time frame, and the external responsiveness is reflected by the
extent to which changes in a measure relate to corresponding changes in
a reference measure (19).
The advantage of having more sensitive measures is that even subtle
changes can be measured in stroke patients with already good
sensory–motor functions. These patients may still have impaired
cognitive functions associated with difficulties in extended ADL tasks
(e.g., cooking, using public transport services).
The aim of this single center, prospective cohort study
was to explore the internal and external responsiveness, floor and
ceiling effects, of the LIMOS motor, and LIMOS cognition and
communication subscales – relative to the widely used FIM motor and FIM
cognition subscales and the BI – in a large cohort of inpatients with
stroke, who received multidisciplinary neurorehabilitation.
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