Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Wednesday, October 26, 2016

Statistical analysis plan for the family-led rehabilitation after stroke in India (ATTEND) trial: A multicenter randomized controlled trial of a new model of stroke rehabilitation compared to usual care

Will be useless unless we finally get a database of stroke rehab protocols with efficacy ratings.
http://wso.sagepub.com/content/early/2016/10/19/1747493016674956.abstract
  1. Laurent Billot1,2
  2. Richard I Lindley1,2⇑
  3. Lisa A Harvey2
  4. Pallab K Maulik3,4
  5. Maree L Hackett1,5
  6. Gudlavalleti VS Murthy6,7
  7. Craig S Anderson1,2
  8. Bindiganavale R Shamanna8
  9. Stephen Jan1
  10. Marion Walker9
  11. Anne Forster10
  12. Peter Langhorne11
  13. Shweta J Verma12
  14. Cynthia Felix3
  15. Mohammed Alim3
  16. Dorcas BC Gandhi12
  17. Jeyaraj Durai Pandian12
  1. 1The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia
  2. 2Sydney Medical School, University of Sydney, Sydney, NSW, Australia
  3. 3Research and Development, George Institute for Global Health India, Hyderabad, Telangana, India
  4. 4The George Institute for Global Health, Oxford University, Oxford, UK
  5. 5College of Health and Wellbeing, University of Central Lancashire, Preston, UK
  6. 6Indian Institute of Public Health, Hyderabad, India
  7. 7Clinical Research Department, London School of Hygiene & Tropical Medicine, London, UK
  8. 8School of Medical Sciences, University of Hyderabad, Hyderabad, Telangana, India
  9. 9School of Medicine, University of Nottingham, Nottingham, UK
  10. 10Academic Unit of Elderly Care and Rehabilitation, Bradford Teaching Hospitals NHS Foundation Trust, University of Leeds, Leeds, UK
  11. 11Academic Section of Geriatric Medicine, Institute of Cardiovascular & Medical Sciences, University of Glasgow, Glasgow, UK
  12. 12Department of Neurology, Christian Medical College, Ludhiana, Punjab, India
  1. Richard I Lindley, The George Institute for Global Health, University of Sydney, Level 3, 50 Bridge St., Sydney, NSW 2000, Australia. Email: richard.lindley@sydney.edu.au

Abstract

Background In low- and middle-income countries, few patients receive organized rehabilitation after stroke, yet the burden of chronic diseases such as stroke is increasing in these countries. Affordable models of effective rehabilitation could have a major impact. The ATTEND trial is evaluating a family-led caregiver delivered rehabilitation program after stroke.
Objective To publish the detailed statistical analysis plan for the ATTEND trial prior to trial unblinding.
Methods Based upon the published registration and protocol, the blinded steering committee and management team, led by the trial statistician, have developed a statistical analysis plan. The plan has been informed by the chosen outcome measures, the data collection forms and knowledge of key baseline data.
Results The resulting statistical analysis plan is consistent with best practice and will allow open and transparent reporting.
Conclusions Publication of the trial statistical analysis plan reduces potential bias in trial reporting, and clearly outlines pre-specified analyses.
Clinical Trial Registrations India CTRI/2013/04/003557; Australian New Zealand Clinical Trials Registry ACTRN1261000078752; Universal Trial Number U1111-1138-6707.
Posted by at
Labels: , , , ,

No comments:

Post a Comment

Subscribe to: Post Comments (Atom)