Deans' stroke musings

Changing stroke rehab and research worldwide now.Time is Brain!Just think of all the trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 493 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It's quite disgusting that this information is not available from every stroke association and doctors group.
My back ground story is here:http://oc1dean.blogspot.com/2010/11/my-background-story_8.html

Tuesday, March 14, 2017

Effects of different exercise strategies and intensities on memory performance and neurogenesis

Maybe there is a protocol in the full article but I doubt it, making this totally useless.
http://journal.frontiersin.org/article/10.3389/fnbeh.2017.00047/abstract
Kai Diederich1*, Anna Bastl1, Heike Wersching2, Anja Teuber2, Jan-Kolja Strecker1, Antje Schmidt1, Jens Minnerup1 and Wolf-Rüdiger Schäbitz3
  • 1Department of Neurology, University of Münster, Germany
  • 2Institute of Epidemiology and Social Medicine, University of Münster, Germany
  • 3Department of Neurology, Evangelisches Krankenhaus Bielefeld, Germany
It is well established that physical exercise affects both hippocampal neurogenesis and memory functions. Until now, distinctive effects of controlled and voluntary training on behavior and neurogenesis as well as interactions between exercise intensity, neurogenesis and memory performance are still elusive. The present study tested the impact of moderate controlled and voluntary training on memory formation and hippocampal neurogenesis and evaluated interactions between exercise performance, learning efficiency and proliferation of progenitor cells in the hippocampus.
Our data show that both controlled and voluntary training augmented spatial learning and promoted hippocampal neurogenesis. Regression analysis revealed a significant linear increase of the amount of new hippocampal neurons with increased exercise intensity. Regression analysis of exercise performance on retention memory performance revealed a quadratic, inverted u-shaped relationship between exercise performance and retention of spatial memory. No association was found between the amount of newborn neurons and memory performance.
Our results demonstrate that controlled training, if performed with an appropriate combination of speed and duration, improves memory performance and neurogenesis. Voluntary exercise elevates neurogenesis dose dependently to high levels. Best cognitive improvement was achieved with moderate exercise performance.
Keywords: Exercise, Hippocampal neurogenesis, Learning, Memory, Regression Analysis
Citation: Diederich K, Bastl A, Wersching H, Teuber A, Strecker J, Schmidt A, Minnerup J and Schäbitz W (2017). Effects of different exercise strategies and intensities on memory performance and neurogenesis. Front. Behav. Neurosci. 11:47. doi: 10.3389/fnbeh.2017.00047

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