- 1Department of Neurology, University of Münster, Germany
- 2Institute of Epidemiology and Social Medicine, University of Münster, Germany
- 3Department of Neurology, Evangelisches Krankenhaus Bielefeld, Germany
Our data show that both controlled and voluntary training augmented spatial learning and promoted hippocampal neurogenesis. Regression analysis revealed a significant linear increase of the amount of new hippocampal neurons with increased exercise intensity. Regression analysis of exercise performance on retention memory performance revealed a quadratic, inverted u-shaped relationship between exercise performance and retention of spatial memory. No association was found between the amount of newborn neurons and memory performance.
Our results demonstrate that controlled training, if performed with an appropriate combination of speed and duration, improves memory performance and neurogenesis. Voluntary exercise elevates neurogenesis dose dependently to high levels. Best cognitive improvement was achieved with moderate exercise performance.
Citation: Diederich K, Bastl A, Wersching H, Teuber A, Strecker J, Schmidt A, Minnerup J and Schäbitz W (2017). Effects of different exercise strategies and intensities on memory performance and neurogenesis. Front. Behav. Neurosci. 11:47. doi: 10.3389/fnbeh.2017.00047