Deans' stroke musings

Changing stroke rehab and research worldwide now.Time is Brain!Just think of all the trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 493 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It's quite disgusting that this information is not available from every stroke association and doctors group.
My back ground story is here:http://oc1dean.blogspot.com/2010/11/my-background-story_8.html

Sunday, March 12, 2017

American Stroke Association honors 10 scientists, researchers for exemplary work

Just reading what is written here, I can see nothing that even comes close to solving all the fucking problems in stroke. We will never get anyplace until the whole goal of stroke research is 100% recovery. I don't care how hard it is or that it is a BHAGs(Big Hairy Audacious Goals) Leaders tackle the hard problems, they don't do useless research as what was honored here.
http://www.cardiovascularbusiness.com/topics/vascular-endovascular/american-stroke-association-honors-10-scientists-researchers-exemplary-work
The American Stroke Association (ASA) recently honored 10 scientists and researchers at its International Stroke Conference in Houston.
The award winners were:
* E. Clarke Haley Jr., MD, of the University of Virginia received the David G. Sherman Award for outstanding lifetime contributions in basic or clinical stroke science. The ASA said he was involved in the initial dose ranging and safety studies of alteplase (tPA) in patients with acute ischemic stroke and helped develop systems to treat acute stroke as an emergency.
* Jaroslaw (Jarek) Aronowski, PhD, of the University of Texas Health Science Center at Houston, received the Thomas Willis Award for significant contributions to clinical stroke research. The ASA said Aronowski is “an international research leader in understanding the cellular and molecular mechanisms underlying the pathology of acute cerebral ischemia, reperfusion injury, and secondary injury after intracerebral hemorrhage with emphasis on the role of transcription factors, neuroinflammation (including role of microglia, neutrophil, and oligodendroglia), stem cell therapy, and the use of ultrasound in tPA-mediated thrombolysis.”
* Steven M. Greenberg, MD, PhD, of Harvard Medical School, received the William M. Feinberg Award for significant contributions on basic science research. The ASA said Greenberg has held numerous leadership positions in stroke and neurology and has authored more than 200 peer-reviewed research articles and 70 chapters, reviews, and editorials in the areas of hemorrhagic stroke and small vessel brain disease.
* Louise D. McCullough, MD, PhD, of McGovern Medical School at UTHealth in Houston, received the Stroke Research Mentoring Award. The ASA said McCullough is known for her work in cerebral vascular disease and identifying sex differences in cell death pathways during stroke.
* Kevin N. Sheth, MD, of the Yale School of Medicine and Yale New Haven Hospital in New Haven, Connecticut, received the Stroke Care in Emergency Medicine Award for the highest scoring emergency medicine abstract. Sheth’s study found that patients younger than 70 years old who have a large ischemic stroke may have improved survival, better functional outcomes and improved quality of life following treatment with intravenous glyburide.
* Steven C. Cramer, MD, of the University of California, Irvine, received the Stroke Rehabilitation Award. Cramer’s study found that a monoclonal antibody known as GSK249320 showed no improvement in gait velocity compared with placebo in pateients recovering from stroke.
* Yejie Shi, MD, PhD, of the University of Pittsburgh, received the Mordecai Y. T. Globus Award for a researcher in training. Shi’s study found that Heat shock protein protected against blood brain barrier disruption after brain ischemia/reperfusion.
* Alessandro Biffi, MD, of Massachusetts General Hospital and Harvard Medical School in Boston, received the Robert G. Siekert Award. The ASA said that “Dr. Biffi’s research team found that the most potent genetic risk factor for cerebral bleeding, the ε4 variant of the APOE gene, amplifies the negative effect of high blood pressure on the well-being of intracerebral hemorrhage survivors.”
* Jennifer Dearborn-Tomazos, MD, MPH, of the Yale School of Medicine in New Haven, Connecticut, received the Vascular Cognitive Impairment Award. Her study found that dietary patterns at midlife were not associated with cognitive decline.
* Yao Yao, PhD, of the University of Minnesota, received the Stroke Basic Science Award. The ASA said that Yao’s study found “strongly suggest that pericyte-derived laminin also actively regulates blood brain barrier integrity and vessel density in an age-dependent manner, but to a lesser extent.”

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