Deans' stroke musings: Racial Differences in Atrial Cardiopathy Phenotypes in Ischemic Stroke Patients

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Thursday, November 26, 2020

Racial Differences in Atrial Cardiopathy Phenotypes in Ischemic Stroke Patients

Please go back to school and figure out the real reason for the differences.

Genetically Speaking, Race Doesn't Exist In Humans October 1998

The latest here:

Racial Differences in Atrial Cardiopathy Phenotypes in Ischemic Stroke Patients

Hooman Kamel, Kathleen Alwell, , , , , , Stacie L. Demel, , Kyle Walsh, Jason Mackey, De Los Rios La Rosa, Felipe, View ORCID ProfileAdam Jasne, Sabreena Slavin, , Opeolu Adeoye, Tehniyat Baig, Monica L. Chen, View ORCID ProfileEmily B. Levitan, Elsayed Z. Soliman, Dawn O. Kleindorfer

First published November 25, 2020, DOI: https://doi.org/10.1212/WNL.0000000000011197

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Abstract

Objective: To test the hypothesis that thrombogenic atrial cardiopathy may be relevant to stroke-related racial disparities, we compared atrial cardiopathy phenotypes between Black versus White ischemic stroke patients.

Methods: We assessed markers of atrial cardiopathy in the Greater Cincinnati/Northern Kentucky Stroke Study, a study of stroke incidence in a population of 1.3 million. We obtained ECGs and reports of echocardiograms performed during evaluation of stroke during the 2010/2015 study periods. Patients with atrial fibrillation (AF) or flutter (AFL) were excluded. Investigators blinded to patients’ characteristics measured P-wave terminal force in ECG lead V₁ (PTFV₁), a marker of left atrial fibrosis and impaired inter-atrial conduction, and abstracted left atrial diameter from echocardiogram reports. Linear regression was used to examine the association between race and atrial cardiopathy markers after adjustment for demographics, body mass index, and vascular comorbidities.

Results: Among 3,426 ischemic stroke cases in Black or White patients without AF/AFL, 2,391 had a left atrial diameter measurement (mean, 3.65 ±0.70 cm). Black race was associated with smaller left atrial diameter in unadjusted (β coefficient, -0.11; 95% CI, -0.17 to -0.05) and adjusted (β, -0.15; 95% CI, -0.21 to -0.09) models. PTFV₁ measurements were available in 3,209 patients (mean, 3,434 ±2,525 μV*ms). Black race was associated with greater PTFV₁ in unadjusted (β, 1.59; 95% CI, 1.21 to 1.97) and adjusted (β, 1.45; 95% CI, 1.00 to 1.80) models.

Conclusions: We found systematic Black-White racial differences in left atrial structure and pathophysiology in a population-based sample of ischemic stroke patients.

Classification of Evidence: This study provides class II evidence that the rate of atrial cardiopathy is greater among Black people with acute stroke compared to White people.