It is what I've been screaming about for years. STROKE HAS NO STRATEGY AND NO LEADERSHIP. Articles like this will do nothing. Our fucking failures of stroke associations have done nothing for decades. Did you somehow miss the 'Stroke is Treatable' meme from World Stroke Day a few years ago? Obviously stroke research is no longer needed. We can repurpose all those researchers into personal care attendants for stroke survivors that somehow didn't obey the meme and fully recover.
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| What a lying piece of shit |
Blowing up Neural Repair for Stroke Recovery
Abstract
The repair and recovery of the brain after stroke is a field that is emerging in its preclinical science and clinical trials. However, recent large, multicenter clinical trials have been negative, and conflicting results emerge on biological targets in preclinical studies. The coalescence of negative clinical translation and confusion in preclinical studies raises the suggestion that perhaps the field of stroke recovery faces a fate similar to stroke neuroprotection, with interesting science ultimately proving difficult to translate to the clinic. This review highlights improvements in 4 areas of the stroke neural repair field that should reorient the field toward successful clinical translation: improvements in rodent genetic models of stroke recovery, consideration of the biological target in stroke recovery, stratification in clinical trials, and the use of appropriate clinical trial end points.
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