'Probably' IS NOT GOOD ENOUGH! Will you please come up with concrete solutions to stroke rehab. THIS EQUIVOCATING HAS TO STOP!
The effects of stroke lesions and timing of rehabilitation on the compensatory movement patterns during stroke recovery
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- PAP
Abstract
Objective
The aims of this study were to distinguish between behavioral compensation and behavioral recovery and to determine the role of stroke lesions and the optimal timing of rehabilitation in true recovery.
Design
Single pellet-reaching test have been performed to analyze both quantitative and qualitative measures of forelimb function in a stroke animal model with lesions in the motor cortex (Mc), somatosensory cortex (Sc), or sensorimotor cortex (SMc). The four gestures of compensatory movement patterns (CMPs) that comprised a reach were head lift, limb withdrawal, pellet chasing, and phantom grasp.
Results
Functional recovery improved in all the stroke groups after rehabilitation (p < 0.001). However, the CMPs of the Mc and Sc stroke groups initially increased and subsequently decreased (p = 0.0054), whereas those of the SMc stroke group increased and persisted (p = 0.0063). In the SMc stroke group, CMPs significantly decreased when training was initiated 5 and 14 days after stroke (p = 0.0083, p = 0.0226, respectively), while they increased and persisted when training was initiated 1 day after stroke.
Conclusion
These findings suggest that true recovery by task-specific training after stroke depends, probably, on the lesion size and the timing of rehabilitation.
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