Deans' stroke musings: Astrocytes build blood vessel scaffolds for long distance neuron migrations

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Thursday, February 2, 2012

Astrocytes build blood vessel scaffolds for long distance neuron migrations

You'll have to read this blogger at the url. Signalling to get migrating neurons to the correct place. Hey, we should be able to mimic this and get new neurons to the damaged areas. Tell your researcher about this. This could be really wonderful for all us chronic survivors.
http://www.guardian.co.uk/science/neurophilosophy/2012/feb/02/1
Star-shaped cells called astrocytes build blood vessel highways for migrating neurons.
The journey undertaken by newborn neurons in the adult mouse brain is like the cellular equivalent of the arduous upstream migration of salmon returning to their hatching river. Soon after being born in the subventricular zone near the back of the brain, these cells embark on a long-distance migration to the front-most tip of the brain. Their final destination – the olfactory bulb – is the furthest point from their birth place, and they travel two-thirds of the length of the brain to get there.
Several years ago, a team of researchers from Canada showed that the pathway for this migration – called the rostral migratory stream – is lined with a scaffold of capillaries, and that the young cells crawl along the blood vessels during their journey. In a follow-up study, they now report that the construction and organization of the blood vessel scaffold is orchestrated by star-shaped cells called astrocytes.