My earliest post on this was back in May 2012
And we still seem to have no stroke protocols on how to use this. Damned lazy everybody in the stroke world. You had better hope you never get a stroke and find out how piss poor the rehab and recovery protocols are.
http://dgnews.docguide.com/treating-uninjured-side-brain-appears-aid-stroke-recovery?
To
maximise stroke recovery, researchers may want to focus more on ways to
support the side of the brain where the injury didn't occur, according
to a study that will be presented at the 2015 International Stroke
Conference (ISC).
“Most studies focus on the stroke area and ways to limit damage in
that area,” said Adviye Ergul, MD, Medical College of Georgia at Georgia
Regents University, Augusta, Georgia.
However, the researchers are among a growing number of scientists
finding that while the opposite side of the brain may not have directly
experienced a stroke, its ability to aid the injured side is affected.
That aid includes endothelial cells that line blood vessels on both
sides of the brain releasing growth factors, which protect neurons, help
ailing ones recover, and prompt the growth of new blood vessels to the
stroke site, which is screaming for blood and oxygen. All this activity
also attracts endogenous stem cells so, even if the new blood vessels
never actually carry blood, they help create what scientists are calling
a “regenerative niche” that can minimise stroke damage.
The uninjured side benefits as well with a boost of growth factors
and maybe even more blood vessels, possibly readying itself to take on
more responsibility.
“We know that blood vessels react a lot to the injury in distant
parts of the brain,” said Dr. Ergul. “Within a few days of a stroke, the
non-damaged side becomes more active and starts taking up, we think,
some of the functions of the damaged side. If you do functional MRIs in
humans, you can see other hemispheres starting to light up more in the
recovery phase within a few days of stroke.”
Patients with diseases such as hypertension and diabetes are at
particular risk for stroke and poor stroke recovery because their
vascular system already has lost some of its innate ability to protect
itself. In the unique domain of the brain, that includes maintaining
super-tight control over blood flow.
“Blood vessels contract to regulate the flow,” said Dr. Ergul. “What
we are seeing in diabetes and hypertension is, for a while, they try to
compensate, but they lose the ability to sense the pressure and regulate
blood flow.”
Without that ability, blood vessels will continue to dilate,
increasing leakiness and bleeding into the brain. In addition, tiny
vessels upstream sense what's happening and contract, further reducing
blood and oxygen supplies to the already fragile stroke area.
“That is why it is so important to regulate the function and also the
new blood vessel formation to generate this nutritive environment,”
said Dr. Ergul.
SOURCE: Medical College of Georgia at Georgia Regents University
No comments:
Post a Comment