Deans' stroke musings: Relationship between carotid arterial properties and cerebral white matter hyperintensities

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Saturday, May 13, 2017

Relationship between carotid arterial properties and cerebral white matter hyperintensities

No clue what this means. I was told I had a bunch of white matter hyperintensities, never was told anything about my carotid stiffness.
https://www.mdlinx.com/internal-medicine/medical-news-article/2017/05/05/carotid-arterial-properties-cerebral-white-matter/7151805/?

Neurology®

Rundek T, et al.

In a cross–sectional study, the physicians aimed to investigate the association of carotid artery stiffness with white matter hyperintensity volume (WMHV) since arterial stiffness is a functional measure of arterial compliance and may be an important marker of cerebrovascular disease. In this multiethnic population, large carotid artery diameters are associated with the greater burden of white matter hyperintensity (WMH). Among Hispanics, the association between increased diameters decreased STRAIN, and greater WMH burden is more pronounced. These relationships imply a potential important pathophysiologic role of extracranial large artery remodeling in the burden of WMH.

Methods

The physicians enrolled 1,166 stroke–free participants. (so useless information for stroke survivors)
They evaluated carotid beta stiffness index (STIFF) by M-mode ultrasound of the common carotid artery and calculated as the ratio of the natural log of the difference between systolic and diastolic blood pressure over STRAIN, a ratio of the difference between carotid systolic and diastolic diameter (DD) divided by DD.
They measured WMHV by fluid-attenuated inversion recovery MRI.
They examined the associations of STIFF, DD, and STRAIN with WMHV using linear regression after adjusting for sociodemographic, lifestyle, and vascular risk factors.

Results

Larger carotid DD was significantly associated with greater log-WMHV (β = 0.09, p = 0.001) in a fully adjusted model.
As per the outcomes, STIFF and STRAIN were not significantly correlated with WMHV.
Among Hispanic participants, STRAIN (β = -1.78, p = 0.002) and DD (β = 0.11, p = 0.001) were both associated with greater log-WMHV, but not among black or white participants in adjusted analyses stratified by race–ethnicity.