- transcranial alternating current stimulation (1)
- transcranial Doppler (2)
- Transcranial Doppler Ultrasound (1)
- Transcranial Electrical Stimulation (2)
- Transcranial laser stimulation (1)
- transcranial micropolarization (1)
- transcranial Random Noise Stimulation (1)
https://www.frontiersin.org/articles/10.3389/fnbeh.2018.00132/abstract
- 1Institute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Japan
ABSTRACT
Transcranial alternating current stimulation (tACS) can be used to modulate oscillatory brain activity. In this study, we investigated whether tACS applied over the primary motor cortex (M1) and cerebellar cortex region improved motor performance. We applied tACS (1.0 mA) to 20 healthy adults while they performed an isometric force task with some visuomotor control using their right index finger. Gamma (70 Hz) oscillations in the experiment 1 or beta (20 Hz) oscillations in the experiment 2 were applied for 30 s over the left M1, right cerebellar hemisphere or both regions (‘M1-Cerebellum’), and errors performing the task were compared. Beta-oscillation tACS did not affect motor performance. With the gamma-oscillation tACS, a negative correlation was found between the difference of error in the M1-Cerebellum condition and the number of errors in the sham condition (P = 0.005, Pearson’s r = −0.597), indicating that motor performance improved with M1-Cerebellum tACS for subjects with low motor performance in the sham condition. Those who performed poorly in the sham condition made significantly fewer errors with M1-Cerebellum tACS (P = 0.004). Thus, for subjects with poorer motor performance, tACS with gamma oscillations applied over the M1 and contralateral cerebellar hemisphere improved their performance.
Transcranial alternating current stimulation (tACS) can be used to modulate oscillatory brain activity. In this study, we investigated whether tACS applied over the primary motor cortex (M1) and cerebellar cortex region improved motor performance. We applied tACS (1.0 mA) to 20 healthy adults while they performed an isometric force task with some visuomotor control using their right index finger. Gamma (70 Hz) oscillations in the experiment 1 or beta (20 Hz) oscillations in the experiment 2 were applied for 30 s over the left M1, right cerebellar hemisphere or both regions (‘M1-Cerebellum’), and errors performing the task were compared. Beta-oscillation tACS did not affect motor performance. With the gamma-oscillation tACS, a negative correlation was found between the difference of error in the M1-Cerebellum condition and the number of errors in the sham condition (P = 0.005, Pearson’s r = −0.597), indicating that motor performance improved with M1-Cerebellum tACS for subjects with low motor performance in the sham condition. Those who performed poorly in the sham condition made significantly fewer errors with M1-Cerebellum tACS (P = 0.004). Thus, for subjects with poorer motor performance, tACS with gamma oscillations applied over the M1 and contralateral cerebellar hemisphere improved their performance.
Keywords:
transcranial alternating current stimulation, gamma oscillations, primary motor cortex, Cerebellar hemisphere, visuo-motor performance
Received: 23 Dec 2017;
Accepted: 12 Jun 2018.
Edited by:
Pietro Pietrini, IMT School for Advanced Studies Lucca, Italy
Reviewed by:
Simone Rossi, University of Siena, Italy
Carmelo Chisari, Azienda Ospedaliero-Universitaria Pisana
Fabio Giovannelli, Università degli Studi di Firenze, Italy
Copyright: © 2018 Miyaguchi, Otsuru, Kojima, Saito, Inukai, Masaki and Onishi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Mr. Shota Miyaguchi, Niigata University of Health and Welfare, Institute for Human Movement and Medical Sciences, Niigata, Japan, miyaguchi@nuhw.ac.jp
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