Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Thursday, June 28, 2018

From Angry Birds to brain mapping: The Gamification of Neuroscience

With 10 million yearly stroke survivors  that number of gamers playing this could easily make great leaps in this knowledge. That great stroke association president should be out there recruiting stroke hospitals to enroll all their stroke patients in this. But we have fucking failures of stroke associations instead, who for some unknown reason have stroke in their name.  It sure is not to solve stroke.

From Angry Birds to brain mapping: The Gamification of Neuroscience

Mouse Retinal Neurons (Type 25), per EyeWire Museum
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In 2012, when Angry Birds was in its prime, Seung had an inspiration.
What if,” he wondered, “we could capture even a small fraction of the mental effort that goes into Angry Birds (for brain mapping)? Think of what we could do.”
Although the initial idea was to use deep learning-based AI tools to reconstruct the neurons, humans were—and still are—better at spotting the patterns of neuronal branches and connectors than machines. Collaborating with Dr. Kevin Slavin, a fellow professor at MIT with a background in game design, Seung tried to make a game about brain tracing as enthralling as a first-person shooter. Spoiler: you can’t … In the game, each player is given a tiny cube of the retinal tissue, about 4.5 microns wide—that’s about the width of a human hair for a 10-by-10 block of cubes. To ensure accuracy, each cell is reviewed by between 5 and 25 gamers—if the results match up, the trace is accepted by the game as being complete. These traces are then fed as “training data” to the deep learning algorithm, which learns to better recognize individual neuronal branches among a giant tangled mass.
Eventually the goal is to automate the entire process. While a pipe dream just five years ago, the power of deep learning in biology has been transformative. A recent study used a powerful algorithm to identify dead neurons in microscope-generated images, a task normally relegated to junior neuroscientist trainees. As more data pours in, EyeWire may eventually learn to self-map, and such a strategy could be adopted to explore other regions in the brain in other species.”

New Study based on EyeWire:

  • A digital “museum” provides dense anatomy and physiology of retinal ganglion cells
  • The inner plexiform layer divides into four sublaminae defined by anatomical criteria
  • The aggregate neurite density of a ganglion cell type is approximately uniform
  • Inner marginal ganglion cells exhibit significantly more sustained visual responses

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