Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Wednesday, February 19, 2020

Efficacy and safety of lanabecestat for treatment of early and mild Alzheimer disease: The amaranth and daybreak-ALZ randomized clinical trials

You might very well need this, assuming your doctor is up-to-date on stroke research and is creating protocols to prevent your dementia. Also assumes your doctor even knows of your need for this.

Your chances of getting dementia.


1. A documented 33% dementia chance post-stroke from an Australian study?   May 2012.


2. Then this study came out and seems to have a range from 17-66%. December 2013.


3. A 20% chance in this research.   July 2013.


4. Dementia Risk Doubled in Patients Following Stroke September 2018 


5. Parkinson’s Disease May Have Link to Stroke March 2017

 

Efficacy and safety of lanabecestat for treatment of early and mild Alzheimer disease: The amaranth and daybreak-ALZ randomized clinical trials

JAMA — Wessels AM, Tariot PN, Zimmer JA, et al. | February 17, 2020
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Researchers investigated whether lanabecestat slows the progression of Alzheimer disease (AD) compared with placebo in patients with early AD (mild cognitive impairment) and mild AD dementia. They performed two multicenter, global, double-blind studies at 257 and 251 centers in 15 and 18 countries or territories, respectively. AMARANTH included 2,218 randomized participants, of whom 539 individuals completed the study. DAYBREAK-ALZ included 1,722 (30.2%) randomized participants, of whom 76 individuals completed the study. In all, the researchers found that although lanabecestat was generally well tolerated, it did not slow cognitive or functional decline in individuals with early or mild AD dementia.
Read the full article on JAMA

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