Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Wednesday, February 3, 2021

EXPRESS: Apathy after stroke: diagnosis, mechanisms, consequences, and treatment

Of course there is apathy after stroke, your doctor knows nothing about 100% recovery and does nothing. The solution is 100% recovery protocols. Your patients wouldn't have time to be apathetic if they knew they had to do 10 million reps of some exercise to get it recovered.  Apathy is a secondary problem, Solve the primary problem of 100% recovery and you don't need research on this topic.  You danced around the question;'Why are stroke survivors apathetic?' Answer: NO STROKE REHAB PROTOCOLS, thus the survivor doesn't see any way to get back to normal.

EXPRESS: Apathy after stroke: diagnosis, mechanisms, consequences, and treatment

  First Published February 2, 2021 Research Article Find in PubMed 

Apathy is a reduction in goal-directed activity in the cognitive, behavioural, emotional, or social domains of a patient's life, and occurs in one out of three patients after stroke. Despite this, apathy is clinically under-recognised and poorly understood. This overview provides a contemporary introduction to apathy in stroke for researchers and practitioners, covering topics including diagnosis, neurobiological mechanisms, associated consequences, and potential treatments for apathy. Apathy is often misdiagnosed as other post-stroke conditions such as depression. Accurate differential diagnosis of apathy, which manifests as reductions in initiative, and depression, which manifests as negative emotionality, is important as it informs prognosis. Research on the neurobiology of apathy suggests that there are few consistent associations between stroke lesion location and the development of apathy. These may be resolved by adopting a network neuroscience approach, which conceptualises of apathy as a pathology arising from structural or functional damage to brain networks underlying motivated behaviour. Importantly, networks can be affected by physiological changes related to stroke, including the acute infarct but also diaschisis and neurodegeneration. Aside from neurobiological changes, apathy is also associated with other negative outcome measures such as functional disability, cognitive impairment, and emotional distress, suggesting that apathy is indicative of a worse prognosis following stroke. Unfortunately, high-quality trials aimed at treating apathy are scarce. Antidepressants may have limited effects on apathy. Acetylcholine and dopamine pharmacotherapy, behavioural interventions, and transcranial magnetic stimulation may be more promising avenues for treatment.

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