Statins may reduce CV events in older patients with stroke

But shouldn't your doctor already been prescribing statins for better recovery since 2003? In my opinion I would say your doctor is incompetent if statins are not immediately prescribed. But I'm not medically trained so just ask your doctor to justify that lack of prescription. My doctor obviously did not extrapolate rat testing to humans and thus did nothing with statins for me in 2006.

1. Statins.

tested in rats from 2003

http://Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke  

Simvastatin Attenuates Stroke-induced Splenic Atrophy and Lung Susceptibility to Spontaneous Bacterial Infection in Mice

Or,

Simvastatin attenuates axonal injury after experimental traumatic brain injury and promotes neurite outgrowth of primary cortical neurons 

October 2012

tested in humans, March, 2011

http://www.medwirenews.com/39/91658/Stroke/Acute_statin_therapy_improves_survival_after_ischemic_stroke.html

And now lost even to the Wayback Machine

So I think this below is the actual research;

Association Between Acute Statin Therapy, Survival, and Improved Functional Outcome After Ischemic Stroke April 2011

The latest here:

Statins may reduce CV events in older patients with stroke

Older patients with ischemic stroke who took statins for 2 years after discharge experienced fewer CV events after hospital discharge compared with those who took them for less than 2 years or not at all, researchers reported in Stroke.

Although statins are frequently initiated in patients aged 80 years and older after an ischemic stroke, evidence of their efficacy in CVD prevention for this population is sparse, so a new analysis was needed, the researchers wrote.

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Geert J. Lefeber, MD, from the department of geriatrics, University Medical Center Utrecht, and the division of pharmacoepidemiology and clinical pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, the Netherlands, and colleagues conducted a retrospective cohort study of 5,910 patients aged 65 years and older hospitalized for a first ischemic stroke from 1999 to 2016 who did not have statin prescriptions in the year before hospitalization.

The primary outcome was a composite of recurrent stroke, MI and CV mortality at 2 years. The primary analysis was for patients aged 80 years or older, but the researchers also analyzed patients aged 65 to 80 years to compare their results with current evidence on statin efficacy.

Among the 3,157 patients aged 80 years and older, compared with those who had a statin prescription of less than 2 years or none at all, those who had a statin prescription for 2 years had lower risk for the primary endpoint (adjusted HR = 0.8; 95% CI, 0.62-1.02) and all-cause mortality (aHR = 0.67; 95% CI, 0.57-0.8).

After correction for the mortality of 23.9% of the patients during the first 2 years, the number needed to treat to prevent one event was 64 for the primary outcome and 19 for all-cause mortality during a median follow-up of 3.9 years.

“To be able to decide whether benefits outweigh harm and which is the most appropriate dose and type of statin, more research is deemed necessary in the oldest old,” Lefeber and colleagues wrote.