This really would be useful if your doctor would stop the 5 causes of the neuronal cascade of death in
the first week. Because my doctor did nothing that first week, he killed off 5.4 billion neurons, I could easily have fully recovered with only 177 million dead neurons.This is just more of the same, blame the survivor for not recovering.
Evidence for a Window of Enhanced Plasticity in the Human Motor Cortex Following Ischemic Stroke
Abstract
Background
In preclinical models, behavioral training early after stroke produces larger gains compared with delayed training. The effects are thought to be mediated by increased and widespread reorganization of synaptic connections in the brain. It is viewed as a period of spontaneous biological recovery during which synaptic plasticity is increased.
Objective
To look for evidence of a similar change in synaptic plasticity in the human brain in the weeks and months after ischemic stroke.
Methods
We used continuous theta burst stimulation (cTBS) to activate synapses repeatedly in the motor cortex. This initiates early stages of synaptic plasticity that temporarily reduces cortical excitability and motor-evoked potential amplitude. Thus, the greater the effect of cTBS on the motor-evoked potential, the greater the inferred level of synaptic plasticity. Data were collected from separate cohorts (Australia and UK). In each cohort, serial measurements were made in the weeks to months following stroke. Data were obtained for the ipsilesional motor cortex in 31 stroke survivors (Australia, 66.6 ± 17.8 years) over 12 months and the contralesional motor cortex in 29 stroke survivors (UK, 68.2 ± 9.8 years) over 6 months.
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