Its been 17 years since tPA has been approved and there still is no knowledge of how effective it is long term.
Who's in charge? Obviously not a stroke survivor. So ask your doctor what your recovery prognosis is based on your use of tPA.
http://www.ncbi.nlm.nih.gov/pubmed/23061414
Abstract
Purpose: Thrombolysis with tissue plasminogen
activator (rtPA) is currently used throughout the world in acute
ischaemic stroke management. In this review, we will explore the status
of our current knowledge about the effects of rtPA on specific
rehabilitation domains and highlight some key knowledge gaps. Methods:
Narrative review of the larger clinical and postmarketing surveillance
studies. Results: To date, most of the previous research into rtPA for
acute ischaemic stroke has focused on safety and efficacy using general
outcome measures and has ceased following patients 90 days after rtPA
administration. This research has provided valuable information about
the safety and efficacy of rtPA and has facilitated the introduction of
rtPA into clinical practice for stroke management.
However there is a
paucity of knowledge about the long-term recovery patterns of patients
post-rtPA, including the effect of rtPA on specific rehabilitation
domains and its impact on post-acute service delivery. Furthermore,
limited information is available about the effect of rtPA on post-stroke
quality of life and participation in society. Conclusion: These
knowledge gaps have substantial implications for the long-term
management of patients by rehabilitation teams. Increasing our knowledge
in these areas may assist us to predict which individuals are most
likely to benefit from thrombolysis with rtPA, and enable us to provide
optimal rehabilitation programs to maximise functional outcomes and
quality of life post-stroke.
No comments:
Post a Comment