theheart.org writeup here;
http://www.medscape.com/viewarticle/818373?t=1
The abstract here:
http://stroke.ahajournals.org/content/early/2013/12/19/STROKEAHA.113.003741.abstract
- Maya J. Lambiase, PhD,
- Laura D. Kubzansky, PhD and
- Rebecca C. Thurston, PhD
+ Author Affiliations
- Correspondence to Maya J. Lambiase, PhD, Department of Psychiatry, University of Pittsburgh School of Medicine, 3811 O’Hara St, Pittsburgh, PA 15213. E-mail MJL106@pitt.edu
Abstract
Background and Purpose—Higher
levels of anxiety are associated with increased risk for coronary heart
disease. However, few studies have investigated
whether anxiety is associated with stroke
risk. The purpose of this study was to examine the association between
anxiety symptoms
and incident stroke in a nationally
representative longitudinal study of the US population.
Methods—Participants
(n=6019) in the First National Health and Nutrition Examination Survey
were assessed at baseline and followed
for 16.29±4.75 years. Multivariate Cox
proportional hazards regression models were used to estimate hazard
ratios and 95%
confidence intervals of incident stroke
associated with a 1 SD increase in anxiety symptoms. Models were
adjusted for standard
cardiovascular risk factors and additionally
for depression.
Results—A total of
419 incident stroke cases were identified from hospital/nursing home
discharge reports and death certificates.
Reporting more anxiety symptoms at baseline
was associated with increased risk of incident stroke after adjusting
for standard
biological and behavioral cardiovascular risk
factors (hazard ratio, 1.14; 95% confidence interval, 1.03–1.25).
Findings persisted
when additionally controlling for depression.
Exploratory analyses considering the role of potential confounding
versus pathway
variables suggested that behavioral factors
may be a key pathway linking anxiety to stroke risk.
Conclusions—Higher
anxiety symptom levels were associated prospectively with increased risk
for incident stroke independent of other risk
factors, including depression. Anxiety is a
modifiable experience that is highly prevalent among the general
population. Its
assessment and treatment may contribute to
developing more effective preventive and intervention strategies for
improving
overall cardiovascular health.
Meditate, meditate, meditate.
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