Deans' stroke musings: Randomized, Sham-Controlled, Feasibility Trial of Hyperbaric Oxygen for Service Members With Postconcussion Syndrome Cognitive and Psychomotor Outcomes 1 Week Postintervention

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Friday, December 27, 2013

Randomized, Sham-Controlled, Feasibility Trial of Hyperbaric Oxygen for Service Members With Postconcussion Syndrome Cognitive and Psychomotor Outcomes 1 Week Postintervention

Since this failed should we now go down the totally opposite route of sending patients to mountaintops for the thin air? As this suggests;

Training the Brain to Survive Stroke

I trust these results more that the possibly biased results from the Israeli HBOT institute here;

Hyperbaric Oxygen Therapy Can Improve Post Concussion Syndrome Years after Mild Traumatic Brain Injury - Randomized Prospective Trial

And the failed HBOT trial here;

http://nnr.sagepub.com/content/early/2013/12/23/1545968313516869.abstract?papetoc

¹Virginia Commonwealth University, Richmond, VA, USA
²Hunter Holmes McGuire Veterans Affairs Medical Center, Richmond, VA, USA
³Richmond Defense and Veterans Brain Injury Center, Richmond, VA, USA
⁴Department of Veterans Affairs, Washington, DC, USA
⁵Navy Medicine Operational Training Center, Pensacola, FL, USA

William C. Walker, MD, Department of PM&R, Virginia Commonwealth University, 1223 East Marshall Street, Richmond, VA 23298, USA. Email: wwalker@mcvh-vcu.edu

Abstract

Background. Mild traumatic brain injury (mTBI) and residual postconcussion syndrome (PCS) are common among combatants of the recent military conflicts in Iraq and Afghanistan. Hyperbaric oxygen (HBO₂) is a proposed treatment but has not been rigorously studied for this condition. Objectives. In a secondary analysis, examine for possible effects on psychomotor (balance and fine motor) and cognitive performance 1 week after an HBO₂ intervention in service members with PCS after mTBI. Methods. A randomized, double-blind, sham control, feasibility trial comparing pretreatment and posttreatment was conducted in 60 male active-duty marines with combat-related mTBI and PCS persisting for 3 to 36 months. Participants were randomized to 1 of 3 preassigned oxygen fractions (10.5%, 75%, or 100%) at 2.0 atmospheres absolute (ATA), resulting in respective groups with an oxygen exposure equivalent to (1) breathing surface air (Sham Air), (2) 100% oxygen at 1.5 ATA (1.5 ATAO2), and (3) 100% oxygen at 2.0 ATA (2.0 ATAO2). Over a 10-week period, participants received 40 hyperbaric chamber sessions of 60 minutes each. Outcome measures, including computerized posturography (balance), grooved pegboard (fine motor speed/dexterity), and multiple neuropsychological tests of cognitive performance, were collected preintervention and 1-week postintervention. Results. Despite the multiple sensitive cognitive and psychomotor measures analyzed at an unadjusted 5% significance level, this study demonstrated no immediate postintervention beneficial effect of exposure to either 1.5 ATAO2 or 2.0 ATAO2 compared with the Sham Air intervention. Conclusions. These results do not support the use of HBO₂ to treat cognitive, balance, or fine motor deficits associated with mTBI and PCS.