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Endovaskuläre Schlaganfallbehandlung vor dem Hintergrund der aktuellen positiven klinischen Studien. Der Nervenarzt , Volume 87(4) , Pgs. 433-448.
NARIC Accession Number: I242433. What's this?
Author(s): G. Thomalla; J. Fiehler.
Publication Year: 2016.
Abstract: This article outlines the benefits of endovascular stroke treatment in stroke patients with occlusion of proximal intracranial arteries. Recently, five independent randomized controlled clinical trials demonstrated the efficacy and safety of this stroke treatment. The five trials, MR CLEAN, ESCAPE, EXTEND-IA, SWIFT-PRIME and REVASCAT, randomized a total of 1287 stroke patients to either standard treatment, which in the majority of patients consisted of intravenous thrombolysis within 4.5 hours of symptom onset or additional endovascular stroke treatment. In all the studies, endovascular treatment resulted in a better clinical outcome with an odds ratio for a better clinical outcome 90 days after stroke ranging between 1.7 and 3.1 and an absolute increase in the proportion of patients with functionally independent outcome between 14% and 31 %. The overwhelming benefit of endovascular treatment mainly results from mechanical thrombectomy using stent retriever devices and starting endovascular treatment within 6 hours of symptom onset in stroke patients.
Descriptor Terms: Clinical trials, Stroke.
Language: German
Geographic Location(s): Europe, Germany.
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Get this Document: http://link.springer.com/article/10.1007/s00115-015-0038-0.
Citation: G. Thomalla, J. Fiehler. (2016). Endovascular stroke treatment following recent positive clinical trials. Endovaskuläre Schlaganfallbehandlung vor dem Hintergrund der aktuellen positiven klinischen Studien. Der Nervenarzt , 87(4), Pgs. 433-448. Retrieved 10/15/2016, from REHABDATA database.
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