https://www.mdlinx.com/internal-medicine/medical-news-article/2017/03/30/cardiovascular-cashew-cholesterol-clinical-trial-hypercholesterolemia/7112741/?news_id=466&newsdt=040317&utm_source=DailyNL&utm_medium=newsletter&utm_content=top-read-article&utm_campaign=article-section&category=nl-digest-last-month&page_id=1
American Journal of Clinical Nutrition
Mah E, et al. – This
randomized, crossover, controlled–feeding trial aimed to examine the
impact of reasonable intakes of cashews on serum lipids in adults with
or at risk of high LDL cholesterol. Researchers observed that the daily
consumption of cashews, when substituted for a high–carbohydrate snack,
might be a simple dietary strategy to help manage total cholesterol and
LDL cholesterol.
Methods
- For the purpose of this study, 51 men and women (aged 21–73 y) with a median LDL-cholesterol concentration of 159 mg/dL (95% CI: 146, 165 mg/dL) at screening consumed typical American diets with cashews (28–64 g/d; 50% of kilocalories from carbohydrate, 18% of kilocalories from protein, and 32% of kilocalories from total fat) or potato chips (control; 54% of kilocalories from carbohydrate, 18% of kilocalories from protein, and 29% of kilocalories from total fat) for 28 d with a ≥ 2-wk washout period.
Results
- According to the findings obtained, consumption of the cashew diet brought about a significantly greater median change from baseline (compared with the control, all P < 0.05) in total cholesterol [-3.9% (95% CI: -9.3%, 1.7%) compared with 0.8% (95% CI: -1.5%, 4.5%), respectively], LDL cholesterol [-4.8% (95% CI: -12.6%, 3.1%) compared with 1.2% (95% CI: -2.3%, 7.8%), respectively], non-HDL cholesterol [-5.3% (95% CI: -8.6%, 2.1%) compared with 1.7% (95% CI: -0.9%, 5.6%), respectively], and the total-cholesterol:HDL-cholesterol ratio [-0.0% (95% CI: -4.3%, 4.8%) compared with 3.4% (95% CI: 0.6%, 5.2%), respectively].
- The results of this study showed that there were no significant differences between diets for HDL cholesterol and triglyceride.
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