Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Tuesday, April 17, 2018

High-intensity statin therapy less likely in women after MI

Should these doctors even be prescribing this?

FDA announces new safety recommendations for high-dose simvastatin June 2011

High-intensity statin therapy less likely in women after MI 




Sanne A.E. Peters
Women were less likely to fill a prescription for high-intensity statins after hospitalization for MI compared with men, according to a study published in the Journal of the American College of Cardiology.
“While the use of high-intensity statins increased in both sexes who filled any statin prescription following MI between 2007 and 2015, our study shows that women continue to be less likely than men to fill a prescription for high-intensity statins,” Sanne A.E. Peters, PhD, research fellow in epidemiology at The George Institute for Global Health at University of Oxford in the United Kingdom, told Cardiology Today. “The underutilization of high-intensity statins in women can be expected to result in a substantial additional number of preventable vascular events.”
Patients with MI hospitalizations
In this retrospective cohort study, researchers reviewed data from 16,898 patients (26% women) younger than 65 years with commercial health insurance and 71,358 patients (49% women) aged at least 66 years with Medicare. Both groups of patients had an overnight hospitalization for MI between 2014 and June 2015. Medicare beneficiaries were alive 30 days after hospital discharge and had continuous insurance coverage during the study.
This study included statin fills of any dosage within 30 days of hospital discharge for MI. High-intensity statins of interest were 40 mg or 80 mg of atorvastatin and 20 mg or 40 mg of rosuvastatin.
Men were more likely to fill a prescription for high-intensity statin after hospital discharged compared with women (56% vs. 47%).
After adjusting for comorbidities, demographic characteristics and health care use, the women-to-men RRs for high-intensity statins were the following:
  • 0.91 for the total population using statins (95% CI, 0.9-0.92);
  • 0.91 in those who did not previously use statins (95% CI, 0.89-0.92);
  • 0.87 for those with prior low- or moderate-intensity statin use (95% CI, 0.85-0.9); and
  • 0.98 in those who previously took high-intensity statins (95% CI, 0.97-1).
Sex disparities in statins
Compared with men, women were less likely to fill prescriptions for high-intensity statins in all subgroups. This disparity was most evident in patients without prevalent comorbid conditions and in the youngest and oldest adults.
“Clinicians should communicate the benefits of high-intensity statins to their female patients in terms of reducing the risk of recurrent MI and discuss possible concerns about side effects,” Peters said in an interview. “Moreover, clinicians themselves should also be aware of the risk of recurrent MI in their female patients and the persistent sex disparity in the utilization of high-intensity statins. Although the ‘Go Red for Women’ initiative and evidence-based guidelines for the prevention of CVD in women may have contributed to the decline in CVD rates in women, the results from the current study suggest that they have not led to elimination of the sex differences in high-intensity statin use after MI among individuals who filled any statin prescription. Further efforts are needed to eliminate sex disparities in high-intensity statin use and to improve the use of high-intensity statin therapy following hospital discharge for MI for all patients.”
In a related editorial, Annabelle Santos Volgman, MD, FACC, FAHA, professor of medicine at Rush Medical College in Chicago, senior attending physician at Rush University Medical Center and medical director of the Rush Heart Center for Women, and colleagues wrote: “We think sex should matter, as well as age, race and ethnicities, when it comes to patient care and adherence to guidelines. Implementation of such sex-specific strategies will improve CVD outcomes for women and, by doing so, may also improve outcomes for men.” – by Darlene Dobkowski
For more information:
Sanne A.E. Peters, PhD, can be reached at

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