Use the labels in the right column to find what you want. Or you can go thru them one by one, there are only 15849 posts. Searching is done in the search box in upper left corner. I blog on anything to do with stroke.DO NOT DO ANYTHING SUGGESTED HERE AS I AM NOT MEDICALLY TRAINED, YOUR DOCTOR IS, LISTEN TO THEM. BUT I BET THEY DON'T KNOW HOW TO GET YOU 100% RECOVERED. I DON'T EITHER, BUT HAVE PLENTY OF QUESTIONS FOR YOUR DOCTOR TO ANSWER.
Deans' stroke musings
Changing stroke rehab and research worldwide now.Time is Brain!Just think of all thetrillions and trillions of neuronsthateach daybecause there areeffective hyperacute therapies besides tPA(only 12% effective). I have 493 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.
What this blog is for:
Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It's quite disgusting that this information is not available from every stroke association and doctors group. My back ground story is here:http://oc1dean.blogspot.com/2010/11/my-background-story_8.html
Tuesday, April 24, 2018
Are Stem Cells the Next Generation of Stroke Therapeutics?
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In this exciting atmosphere of having new endovascular treatment options for our acute stroke patients, the Stroke journal commissioned a focused update on the application of stem cells and cell-based therapies given new advancements in our mechanistic understanding of stem cells and given the launch of phase 2B and 3 efficacy trials. After initial attempts in cell transplantation approaches for patients with chronic subcortical strokes in the 1990s, the field of stem cells in stroke shifted focus over the past 20 years, resulting in new therapeutic strategies using easily accessible cell types that modulate immune responses to injury and amplify endogenous repair processes. We have learned that the secretomes and microparticles that cell therapies release may be the principal mediators of their therapeutic effects.
Partnerships between industry and academia have been instrumental in advancing this field. Only a select few companies have sustained investments to carry out studies from preclinical development all the way to efficacy trials. Notably, Athersys has initiated two phase 3 efficacy trials on its cell-based platform, MultiStem, for patients with acute ischemic stroke, whereas ReNeuron and SanBio are now in phase 2B stages for patients with chronic stroke.