Useless until your stroke hospital gets the protocol for using this. They've had 4 years and I bet nothing was accomplished in those 4 years. Incompetence reigns supreme in your stroke hospital.
A Randomized Controlled Trial of EEG-Based Motor Imagery Brain-Computer Interface Robotic Rehabilitation for Stroke
Show all authors
Kai Keng Ang1
, Karen Sui Geok Chua2
, Kok Soon Phua1
,
1Institute for Infocomm and Research, Agency of Science, Technology and Research, Singapore
See all articles by this author
See all articles by this author
Search Google Scholar for this author
2Department of Rehabilitation Medicine, Tan Tock Seng Hospital Rehabilitation Centre, Singapore
See all articles by this author
See all articles by this author
Search Google Scholar for this author
1Institute for Infocomm and Research, Agency of Science, Technology and Research, Singapore
See all articles by this author
See all articles by this author
Search Google Scholar for this author
Chuanchu Wang1
, Zheng Yang Chin1
, Christopher Wee Keong Kuah2
, Wilson Low3
, Cuntai Guan1
...
1Institute for Infocomm and Research, Agency of Science, Technology and Research, Singapore
See all articles by this author
See all articles by this author
Search Google Scholar for this author
1Institute for Infocomm and Research, Agency of Science, Technology and Research, Singapore
See all articles by this author
See all articles by this author
Search Google Scholar for this author
2Department of Rehabilitation Medicine, Tan Tock Seng Hospital Rehabilitation Centre, Singapore
See all articles by this author
See all articles by this author
Search Google Scholar for this author
3Clinical Research Unit, Tan Tock Seng Hospital, Singapore
See all articles by this author
See all articles by this author
Search Google Scholar for this author
1Institute for Infocomm and Research, Agency of Science, Technology and Research, Singapore
See all articles by this author
See all articles by this author
Search Google Scholar for this author
Article Information
Volume: 46 issue: 4, page(s): 310-320
Article first published online: April 21, 2014; Issue published: October 1, 2015
https://doi.org/10.1177/1550059414522229
Kai Keng Ang1, Karen Sui Geok Chua2, Kok Soon Phua1, Chuanchu Wang1, Zheng Yang Chin1, Christopher Wee Keong Kuah2, Wilson Low3, Cuntai Guan1
1Institute for Infocomm and Research, Agency of Science, Technology and Research, Singapore
2Department of Rehabilitation Medicine, Tan Tock Seng Hospital Rehabilitation Centre, Singapore
3Clinical Research Unit, Tan Tock Seng Hospital, Singapore
Corresponding Author: Kai Keng Ang, Institute for Infocomm and Research, Agency of Science, Technology and Research (A*STAR), 1 Fusionopolis Way, #21-01 Connexis (South Tower), 138632, Singapore. Email: kkang@i2r. a-star. edu. sg
Abstract
Section:
Electroencephalography (EEG)–based motor imagery (MI) brain-computer interface (BCI) technology has the potential to restore motor function by inducing activity-dependent brain plasticity. The purpose of this study was to investigate the efficacy of an EEG-based MI BCI system coupled with MIT-Manus shoulder-elbow robotic feedback (BCI-Manus) for subjects with chronic stroke with upper-limb hemiparesis. In this single-blind, randomized trial, 26 hemiplegic subjects (Fugl-Meyer Assessment of Motor Recovery After Stroke [FMMA] score, 4-40; 16 men; mean age, 51.4 years; mean stroke duration, 297.4 days), prescreened with the ability to use the MI BCI, were randomly allocated to BCI-Manus or Manus therapy, lasting 18 hours over 4 weeks. Efficacy was measured using upper-extremity FMMA scores at weeks 0, 2, 4 and 12. ElEG data from subjects allocated to BCI-Manus were quantified using the revised brain symmetry index (rBSI) and analyzed for correlation with the improvements in FMMA score. Eleven and 15 subjects underwent BCI-Manus and Manus therapy, respectively. One subject in the Manus group dropped out. Mean total FMMA scores at weeks 0, 2, 4, and 12 weeks improved for both groups: 26.3 ± 10.3, 27.4 ± 12.0, 30.8 ± 13.8, and 31.5 ± 13.5 for BCI-Manus and 26.6 ± 18.9, 29.9 ± 20.6, 32.9 ± 21.4, and 33.9 ± 20.2 for Manus, with no intergroup differences (P = .51). More subjects attained further gains in FMMA scores at week 12 from BCI-Manus (7 of 11 [63.6%]) than Manus (5 of 14 [35.7%]). A negative correlation was found between the rBSI and FMMA score improvement (P = .044). BCI-Manus therapy was well tolerated and not associated with adverse events. In conclusion, BCI-Manus therapy is effective and safe for arm rehabilitation after severe poststroke hemiparesis. Motor gains were comparable to those attained with intensive robotic therapy (1,040 repetitions/session) despite reduced arm exercise repetitions using EEG-based MI-triggered robotic feedback (136 repetitions/session). The correlation of rBSI with motor improvements suggests that the rBSI can be used as a prognostic measure for BCI-based stroke rehabilitation.
No comments:
Post a Comment