TORONTO, July 13, 2018 (GLOBE NEWSWIRE) -- Scythian Biosciences Corp. (the "Company" or “Scythian”) (TSXV:SCYB) (Frankfurt:9SB) (OTC – Nasdaq Intl:SCCYF) and its partners at the University of Miami Miller School of Medicine are pleased to announce the results of a pre-clinical study evaluating the safety and efficacy of a cannabis derived combination therapy in the treatment of mild to moderate traumatic brain injury (TBI) in rodents.
The pilot study indicates an improvement in the cognitive functions of animals treated with a cannabinoid (CBD) derived combination therapy compared to being treated with a vehicle, CBD alone, and HU211 alone. Further, there were no adverse effects from either the combination therapy (CBD + HU211) or the individual components observed by scientists at the University of Miami Miller School of Medicine.
“We are encouraged by the initial findings of this study which provide persuasive and encouraging evidence that warrants the continuation of this research program,” said CEO Rob Reid.  “We are just beginning to tap the potential healing power of medical cannabis and exploring its growing number of benefits.” 
The researchers feel these results are a promising first step in their systematic evaluation of the use of CBD in the treatment of mild to moderate traumatic brain injury (TBI). These data points lay an important basic science foundation to examine the use of novel cannabinoid compounds on TBI related outcomes and provides the necessary groundwork to proceed with additional pilot studies designed to systematically explore whether this compound can mitigate the deleterious physical, cognitive and behavioral changes following mild to moderate TBI.
“These findings, which represent the initial results from our TBI study using this novel combination therapy merit further investigation in other pre-clinical models of brain injury including concussion.  More work needs to be done, including evaluating the use of these compounds on other injury models and in preparing for a clinical trial of these compounds if their use is supported by the ongoing basic science research,” said Helen M. Bramlett, Ph.D. Professor, Director, Undergraduate Neuroscience Program, Department of Neurological Surgery and The Miami Project to Cure Paralysis.
"There needs to be more systematic research in this field in order to study the neuroprotective properties of CBD and to improve treatment for those sustaining mild to moderate TBI and concussion. We are excited by these results, although in the early stages, shows positive pre-clinical work which shows promise to hopefully lead us to future clinical trials,” said Gillian A. Hotz, Ph.D., University of Miami Miller School of Medicine Research Professor, Department of Neurological Surgery, Director, KiDZ Neuroscience Center at The Miami Project to Cure Paralysis and Director, Concussion Program University of Miami Sports Medicine Institute.
The University of Miami Miller School of Medicine team, led by study principal investigator Gillian Hotz, Bonnie Levin Ph.D., Professor, Director, Division of Neuropsychology, Department of Neurology, Helen M. Bramlett, Michael Hoffer, M.D., Director of the Vestibular and Balance Program in the Department of Otolaryngology and W. Dalton Dietrich, Ph.D., Scientific Director, The Miami Project to Cure Paralysis, Kinetic Concepts Distinguished Chair in Neurosurgery, Senior Associate Dean for Discovery Science, Professor, Neurological Surgery, Neurology, Cell Biology and Biomedical Engineering, has been working on a series of pre-clinical trials to study the effects of the drug on a model system.  At the same time, the team has been examining critical metrics for a possible planned clinical trial in the future.  The team represents a multi-disciplinary effort from University of Miami Miller School of Medicine across the Departments of Neurosurgery, Neurology, Otolaryngology, Sports Medicine Institute and The Miami Project to Cure Paralysis.
About Scythian Biosciences Corp.
Scythian is an international cannabis company with a focus on the world’s leading markets outside of Canada. Its fast tracked growth has come through a number strategic initiatives and partnerships in cultivation, distribution and branded products across Europe, United States, South America and the Caribbean. These significant endeavours complement the company’s R&D partnerships with some of the world’s leading universities. It is this comprehensive approach that is positioning Scythian as a future global frontrunner in the medical cannabis industry.
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CONTACT INFORMATION
Scythian Biosciences Corp.
Rob Reid, CEO
Phone: (212) 729-9208
Email: info@scythianbio.com
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