For laypeople this is completely not understandable, great word salad though, which is going to limit your advancement if you can't explain anything.
Blood pressure and risk of dementia and its subtypes: A historical cohort study with long-term follow up in 2.6 million people
European Journal of Neurology — Gregson J, et al. | June 27, 2019
Because blood pressure (BP) is
thought to fall during the prodromal phase of dementia development,
researchers studied correlations by categories of time since BP
measurement (< 5 years, 5-10 years, > 10 years), and by dementia
subtypes. To explore the connection between BP and physician-diagnosed
dementia, Poisson regression models were used. The study sample
consisted of 2,593,629 individuals from the United Kingdom Clinical
Practice Research Database (aged ≥ 40 years) with a BP measurement
between 1992 and 2011, and no prior record of dementia. Investigators
found 65,618 cases of dementia during a median follow up of 8.2 years:
49,161 Alzheimer's, 13,816 vascular dementia, and 2,541 other subtypes.
In the short-term, elevated BP is linked to a reduced risk of dementia,
possibly due to reverse causation. BP's long-term dementia associations
are less marked and vary by subtype of dementia.
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