Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Tuesday, January 26, 2021

Aging faster: worry and rumination in late life are associated with greater brain age

 You are going to need to know how to stop your rumination about the disaster of your stroke. Your doctor's responsibility is to give  protocols to stop rumination.  Or she could do it the right way by solving the primary problem. 100% recovery.

Aging faster: worry and rumination in late life are associated with greater brain age

Highlights

Brain age is a machine learning derived marker of accelerated aging.

Greater brain age associated with more worry and rumination, and less suppression.

Women had lower brain age compared to men, replicating past studies on brain age.

Past work showed that negative repetitive thoughts are related to greater AD risk.

There is need for developing interventions targeting repetitive negative thoughts.

Abstract

Older adults with anxiety have lower gray matter brain volume – a component of accelerated aging. We have previously validated a machine learning model to predict brain age, an estimate of an individual’s age based on voxel-wise gray matter images. We investigated associations between brain age and anxiety, depression, stress, and emotion regulation. We recruited 78 participants (≥50yrs) along a wide range of worry severity. We collected imaging data and computed voxel-wise gray matter images, which was input into an existing machine learning model to estimate brain age. We conducted a multivariable linear regression between brain age and age, sex, race, education, worry, anxiety, depression, rumination, neuroticism, stress, reappraisal, and suppression. We found that greater brain age was significantly associated with greater age, male sex, greater worry, greater rumination, and lower suppression. Male sex, worry and rumination are associated with accelerated aging in late life and expressive suppression may have a protective effect. These results provide evidence for the transdiagnostic model of negative repetitive thoughts, which are associated with cognitive decline, amyloid, and tau.

 

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