Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Saturday, October 25, 2025

Photobiomodulation in stroke prevention and treatment: neuroprotective mechanisms and therapeutic challenges

 

Didn't your competent? doctor figure out a protocol on this 13 years ago? NO? So you DON'T have a functioning stroke doctor? Why are you seeing them?

Photobiomodulation in stroke prevention and treatment: neuroprotective mechanisms and therapeutic challenges


Yuecheng Li 1, Lei Zhang 1, Jiaqiang Lin 1, Luodan Yang 2, Rui Duan 3
Affiliations 

Abstract

Stroke remains a leading cause of disability globally, resulting from sudden interruptions in blood flow to the brain. While acute treatments have been a primary focus, there is increasing interest in the potential of photobiomodulation (PBM) therapy for both stroke prevention and rehabilitation. PBM harnesses specific wavelengths of light to stimulate biological processes that can protect neural tissue and promote recovery. Recent evidence suggests that PBM therapy can lead to significant improvements in motor function for individuals experiencing post-stroke hemiparesis, especially when combined with treatments targeting both the brain and skeletal muscles. This review explores the mechanisms underlying PBM therapy, emphasizing the role of key chromophores, such as cytochrome c oxidase and calcium ion channels. It also highlights the therapeutic effects of red and near-infrared light, while considering water as a crucial chromophore that may enhance treatment efficacy. The review addresses challenges related to light penetration during various stages of stroke and underscores the importance of optimizing treatment parameters, including the use of multi-site irradiation and advanced delivery systems involving nanoparticles. By consolidating the current understanding of PBM therapy, this review aims to illustrate its promise as a non-invasive approach for stroke prevention and rehabilitation. It advocates for the development of standardized clinical protocols and personalized PBM strategies that incorporate different wavelengths and combination therapies to improve treatment outcomes. Ultimately, this review emphasizes the potential of PBM therapy to address the complex challenges posed by stroke and advance clinical practice.


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