Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Wednesday, November 26, 2025

Harnessing the Power of Low-Intensity Focused Ultrasound Stimulation in Stroke: Modulating Immune Response

 

And all these from earlier research means our stroke leaders should be focusing on this and getting protocols ready for widespread use. But since we have NO STROKE LEADERSHIP; not a damn thing will be done. Don't plan of having a stroke anytime soon and make damn sure your children and grandchildren never have strokes.  You'll have to hope you win against the odds of getting to 100% recovery when you are the 1 in 4 per WHO that has a stroke.


Combined therapy of focused ultrasound and aducanumab induces neurogenesis and decreases of beta-amyloid plaques in a mouse model of Alzheimer’s disease August 2022 

And this from July 2018:

Ultrasound Could Help Improve Dementia Symptoms July 2018 

And this from December 2021:

Using Micro-Ultrasound to Investigate the Effectiveness of Short-Term Rehabilitation following Focal Ischemic Stroke December 2021 

Alzheimer’s breakthrough uses ultrasound technology March 2015

 

The latest here: 

Harnessing the Power of Low-Intensity Focused Ultrasound Stimulation in Stroke: Modulating Immune Response

 

Abstract


Stroke remains a leading cause of death and disability worldwide, with both ischemic and hemorrhagic subtypes triggering complex inflammatory cascades that exacerbate neuronal damage and impede recovery. Despite significant advances in understanding stroke pathophysiology, therapeutic interventions targeting neuroinflammation have shown limited clinical efficacy. Low-intensity focused ultrasound stimulation has emerged as a noninvasive neuromodulatory approach with promising potential for modulating poststroke immune responses and promoting neuroprotection. Low-intensity focused ultrasound stimulation can enhance stroke recovery by modulating immune cell activity and alleviating neuroinflammation. This review explores the multifaceted interplay between low-intensity focused ultrasound stimulation and the immune response in stroke, examining how ultrasound parameters can be optimized to achieve anti-inflammatory effects. We discuss preclinical evidence that highlights the therapeutic benefits of low-intensity focused ultrasound stimulation in stroke models, elucidate underlying mechanisms of action, and consider translational prospects and challenges for clinical application in patients with stroke.

Graphical Abstract

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