Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Monday, November 24, 2025

Ferroptosis biomarkers predict the outcomes of patients with acute ischemic stroke undergoing endovascular thrombectomy

 Predictions like this are absolutely fucking useless since they assume the status quo of failure to get survivors recovered. DO THE GODDAMN RESEARCH THAT GETS SURVIVORS RECOVERED! That is the research needed, not this useless crap!

Your doctor, if competent at all, should have already known about ferroptosis from this research from September 2017.  And should have initiated stroke treatment interventions from it. But s/he fucking failed at their job, right?

 Dementia research leads to potential new stroke treatment

The latest here:

Ferroptosis biomarkers predict the outcomes of patients with acute ischemic stroke undergoing endovascular thrombectomy


Scientific Reports volume 15, Article number: 39510 (2025) Cite this article

Abstract

Ferroptosis contributes to ischemic injury in basic experiments, but the roles of ferroptosis in patients with acute ischemic stroke (AIS) who received reperfusion therapy were unclear. This study prospectively enrolled patients with AIS who underwent endovascular thrombectomy (EVT) and non-stroke controls between February 2019 and May 2023. The plasma levels of three ferroptosis biomarkers—heat shock protein 70 (HSP70), ferritin, and acyl-CoA synthetase long-chain family member 4 (ACSL4)—were measured at pre-EVT, immediately post-EVT, and 24 h post-EVT in stroke patients. Outcomes were assessed using modified Rankin Scale (mRS) score and mortality at 3 months. The study enrolled 150 stroke patients and 50 controls. Stroke patients had higher HSP70 levels than controls. Functional independence (mRS score 0–2) was achieved in 42.5% of 134 followed patients, which was inversely associated with ACSL4 level at 24 h (adjusted odds ratio [aOR] 0.12, 95% confidence interval [CI] 0.03–0.56, P = 0.007) in multivariate logistic regression analyses. Morality occurred in 17.2% of these patients, which was inversely associated with pre-EVT HSP70 level (aOR 0.13, 95% CI 0.02–0.98, P = 0.048). In conclusion, ferroptosis was involved in patients with AIS who underwent EVT, and the plasma levels of ACSL4 and HSP70 were significantly associated with clinical outcomes.


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