Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Wednesday, October 21, 2015

Treatment with adipose stem cells in a patient with moderate Alzheimer's disease: case report

Possible usefulness.
https://www.dovepress.com/articles.php?article_id=24177
Authors Tsolaki M, Zygouris S, Tsoutsikas V, Anestakis D, Koliakos G
Received 22 July 2015
Accepted for publication 18 August 2015
Published 15 October 2015 Volume 2015:3 Pages 115—120
DOI http://dx.doi.org/10.2147/JN.S92869
Checked for plagiarism Yes
Review by Single-blind
Peer reviewers approved by Dr Saberi Hooshang
Peer reviewer comments 3
Editor who approved publication: Prof. Dr. Hari Shanker Sharma
Magda Tsolaki,1,2 Stelios Zygouris,1,3 Vassilis Tsoutsikas,2 Doxakis Anestakis,2,4,5 George Koliakos6,7

1Third Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece; 2Greek Association of Alzheimer's Disease and Related Disorders, Thessaloniki, Greece; 3CND+, 4Laboratory of Forensic Medicine and Toxicology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece; 5Laboratory of General Biology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece; 6Biohellenika Stem Cells Bank, Thessaloniki, Greece; 7Department of Biological Chemistry, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece


Objective: This article presents the case of a female patient with Alzheimer's disease (AD). The patient was treated with cholinesterase inhibitors and also with intravenous administration of autologous adipose stem cells.
Methods: The patient was assessed with a neuropsychological battery including measures of general cognition, functional problems, neuropsychiatric issues, memory (verbal, visual and episodic), verbal learning and visuospatial abilities. Magnetic resonance imaging (MRI) scans were conducted before and after the treatment with stem cells.
Results: A transient and mild improvement of scores in measures of general cognition and neuropsychiatric issues was evident. A rapid deterioration followed the initial improvement. The first MRI scan showed ischemic areas in periventricular white matter of both hemispheres, as well as in both temporal and parietal lobes. The second MRI scan revealed the same picture with no significant changes.
Conclusion: This case report indicates that the administration of stem cells is feasible in a clinical setting however its effectiveness in the treatment of AD is uncertain. The improvement of the patient's condition highlights the potential therapeutic action of stem cells, however the rapid deterioration poses questions concerning limited effectiveness or possible side effects of stem cell administration. Further research is needed in order to clarify the method's effectiveness.

Keywords: Alzheimer's disease, stem cells, case report, dementia
Download Article [PDF] 

No comments:

Post a Comment