http://www.healthcarepublication.com/treatment-for-stroke-repair-brain/
Researchers from the University of
Manchester have developed a new treatment that could limit the damage
caused by treatment for stroke and also promote repair in the affected
area of the brain. What’s more, the drug they’re using has already been
clinically approved.
The researchers’ study is published in Brain, Behavior and Immunity, and
it recounts how they developed their treatment using mice bred to
develop ischemic treatment for stroke, the most prevalent type of stroke
and one that occurs when an artery that supplies oxygen-rich blood to
the brain is blocked. Soon after the mice experienced a stroke,
the researchers treated them with interleukin-1 receptor antagonist
(IL-1Ra), an anti-inflammatory drug that is already licensed for use in
treating rheumatoid arthritis.
They noticed a reduction in the amount
of brain damage typically observed after a treatment for stroke and also
noted that the drug boosted neurogenesis (the birth of new cells) in
the areas that did experience brain damage in the days following the
treatment. The mice even regained the motor skills they lost due to the
stroke.
The researchers’ study is published in Brain, Behavior and Immunity, and
it recounts how they developed their treatment using mice bred to
develop ischemic treatment for stroke, the most prevalent type of stroke
and one that occurs when an artery that supplies oxygen-rich blood to
the brain is blocked. Soon after the mice experienced a stroke,
the researchers treated them with interleukin-1 receptor antagonist
(IL-1Ra), an anti-inflammatory drug that is already licensed for use in
treating rheumatoid arthritis.
They noticed a reduction in the amount
of brain damage typically observed after a treatment for stroke and also
noted that the drug boosted neurogenesis (the birth of new cells) in
the areas that did experience brain damage in the days following the
treatment. The mice even regained the motor skills they lost due to the
stroke.
HOPE FOR A CURE
Treatment for stroke is the fifth
leading cause of death in the United States and about 800,000 people
suffer from one each year, according to the Centers for Disease Control
and Prevention (CDC). They occur when the flow of blood to the brain is
interrupted, usually due to a blood clot or a buildup of fat that broke
off from the arteries and traveled to the brain. The condition is
extremely dangerous because brain cells can die within a few minutes of
the treatment for stroke, causing permanent damage or even death.
Must Read: What is stroke? Treatment for stroke
We still don’t have a treatment to
adequately prevent or reverse the damage to the brain caused by
treatment for stroke, but the Manchester researchers believe that their
development could change that. Though they are still in early stages of
clinical trials, they hope to eventually move on to larger trials and
eventually human testing. Together with other research, this new study
offers hope to the thousands of people whose lives are impacted by
strokes worldwide.
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