- A systematic literature search was performed until June 2015 on prospective studies that looked at milk consumption, all-cause mortality, coronary heart disease and stroke.
- After that, random-effect meta-analyses were performed with dose-response.
- 21 studies including 19 cohorts were incorporated in this meta-analysis, 11 on all-cause mortality, 9 on coronary heart disease, and 10 on stroke.
- Researchers observed that milk intake ranged from 0 to 850 mL/d.
- The results of this study showed that the summary relative risk (SRR) for 200 mL/d milk consumption was 1.01 (95% CI: 0.96–1.06) for all-cause mortality, 1.01 (95% CI: 0.98–1.05) for fatal and non fatal coronary heart disease, and 0.91 (95% CI: 0.82–1.02) for fatal and non fatal stroke.
- It was observed in the findings that stratified analyses by age, Body Mass Index, total energy intake and physical acitivity did not alter the SRR estimates.
- According to the outcomes of this work, the possibility of publication bias was found for all cause mortality and for stroke, demonstrating a gap in information that could have proposed a higher risk of these conditions with expanded milk consumption.