Your doctor, if any good at all, will be telling you this in the next couple of weeks.
http://dgnews.docguide.com/body-weight-fluctuations-linked-more-deaths-patients-coronary-artery-disease?
Repeated cycles of weight loss and gain may be linked to higher risk
for stroke, myocardial infarction (MI), and death in people with
pre-existing coronary artery disease, according to a study published
online in the New England Journal of Medicine.
The study was the first to measure the effect of weight cycling on health outcomes in people with pre-existing heart disease.
People with the largest weight changes were found to experience 136 %
more strokes, 117% more MIs, and 124% more deaths than those with the
smallest shifts in weight. Those in the high-fluctuation group had
weight changes as large as 3.9 kg (~8.6 lbs), while weight varied by
around 0.9 kg (~2 lbs) in the group with the smallest shifts in weight.
“Our findings suggest that we need to be concerned about weight
fluctuation in this group that is already at high risk due to coronary
disease,” said lead author Sripal Bangalore, MD, Cardiovascular Clinical
Research Center, NYU Langone Medical Center, New York, New York.
“Even though this analysis was not designed to find out the causes of
increased risk with body weight fluctuations, we need to examine how we
can help Americans keep weight off, rather than having it go up and
down.”
The researchers reviewed data on 9,509 men and women with coronary
artery disease who participated in the Treating to New Targets trial,
which originally concluded in 2005. Study participants were aged 35 to
75 years and all had coronary artery disease, high cholesterol levels,
and some history of heart problems. Half were being treated with
cholesterol-lowering drugs in intensive doses to see if this resulted in
fewer deaths. All patients were monitored for a median of 4.7 years.
The analysis linked shifts in body weight to statistically
significant differences in outcomes only in people who were overweight
or obese at the beginning of the study, but not for people who started
with normal weight.
Body weight changes were also strongly linked to an increase in newly
diagnosed diabetes, and associations persisted regardless of a person’s
average body weight and traditional risk factors for heart disease.
The researchers cautioned that their re-analysis does not show a
cause-and-effect relationship between weight cycling and poor outcomes,
but only an association. The authors also recognise that they were
unable to tell if people lost weight intentionally, unintentionally, or
due to illness, or if any eventual heart problems resulted directly from
the weight loss, change in weight, or illness.
Dr. Bangalore hopes that the current findings will lead to further
study of weight fluctuation in people with coronary artery disease and
to the development of related practice guidelines once all the evidence
is in.
SOURCE: NYU Langone Medical Center
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