Deans' stroke musings

Changing stroke rehab and research worldwide now.Time is Brain!Just think of all the trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 493 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It's quite disgusting that this information is not available from every stroke association and doctors group.
My back ground story is here:

Thursday, April 6, 2017

Body Weight Fluctuations Linked to More Deaths in Patients With Coronary Artery Disease

Your doctor, if any good at all, will be telling you this in the next couple of weeks.
Repeated cycles of weight loss and gain may be linked to higher risk for stroke, myocardial infarction (MI), and death in people with pre-existing coronary artery disease, according to a study published online in the New England Journal of Medicine.
The study was the first to measure the effect of weight cycling on health outcomes in people with pre-existing heart disease.
People with the largest weight changes were found to experience 136 % more strokes, 117% more MIs, and 124% more deaths than those with the smallest shifts in weight. Those in the high-fluctuation group had weight changes as large as 3.9 kg (~8.6 lbs), while weight varied by around 0.9 kg (~2 lbs) in the group with the smallest shifts in weight.
“Our findings suggest that we need to be concerned about weight fluctuation in this group that is already at high risk due to coronary disease,” said lead author Sripal Bangalore, MD, Cardiovascular Clinical Research Center, NYU Langone Medical Center, New York, New York.
“Even though this analysis was not designed to find out the causes of increased risk with body weight fluctuations, we need to examine how we can help Americans keep weight off, rather than having it go up and down.”
The researchers reviewed data on 9,509 men and women with coronary artery disease who participated in the Treating to New Targets trial, which originally concluded in 2005. Study participants were aged 35 to 75 years and all had coronary artery disease, high cholesterol levels, and some history of heart problems. Half were being treated with cholesterol-lowering drugs in intensive doses to see if this resulted in fewer deaths. All patients were monitored for a median of 4.7 years.
The analysis linked shifts in body weight to statistically significant differences in outcomes only in people who were overweight or obese at the beginning of the study, but not for people who started with normal weight.
Body weight changes were also strongly linked to an increase in newly diagnosed diabetes, and associations persisted regardless of a person’s average body weight and traditional risk factors for heart disease.
The researchers cautioned that their re-analysis does not show a cause-and-effect relationship between weight cycling and poor outcomes, but only an association. The authors also recognise that they were unable to tell if people lost weight intentionally, unintentionally, or due to illness, or if any eventual heart problems resulted directly from the weight loss, change in weight, or illness.
Dr. Bangalore hopes that the current findings will lead to further study of weight fluctuation in people with coronary artery disease and to the development of related practice guidelines once all the evidence is in.
SOURCE: NYU Langone Medical Center

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