Use the labels in the right column to find what you want. Or you can go thru them one by one, there are only 13380 posts. Searching is done in the search box in upper left corner. I blog on anything to do with stroke.DO NOT DO ANYTHING SUGGESTED HERE AS I AM NOT MEDICALLY TRAINED, YOUR DOCTOR IS, LISTEN TO THEM. BUT I BET THEY DON'T KNOW HOW TO GET YOU 100% RECOVERED. I DON'T EITHER, BUT HAVE PLENTY OF QUESTIONS FOR YOUR DOCTOR TO ANSWER.
Deans' stroke musings
Changing stroke rehab and research worldwide now.Time is Brain!Just think of all thetrillions and trillions of neuronsthateach daybecause there areeffective hyperacute therapies besides tPA(only 12% effective). I have 493 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.
What this blog is for:
Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It's quite disgusting that this information is not available from every stroke association and doctors group. My back ground story is here:http://oc1dean.blogspot.com/2010/11/my-background-story_8.html
Tuesday, July 18, 2017
Non-invasive remote ischemic postconditioning stimulates neurogenesis during the recovery phase after cerebral ischemia
In the 8 years since this earlier one came out has anything been done to get this into a stroke protocol? Does no one think about all the survivors needing this to help get recovered?
postconditioning (IPostC) has been reported to have neuroprotection
against ischemic diseases, and one cycle of IPostC induces neurogenesis
when treated nearby. To expanding these effects, we explored the effects
of repetitively remote IPostC (NRIPostC) on neurogenesis in the
subgranular zone (SGZ) and subentricular zone (SVZ) during stroke
recovery. Animals underwent transient cerebral ischemia were treated
with vehicle or NRIPostC immediately after reperfusion. Neurological
severity scores, infarct size, neurogenesis, and protein expression
levels of nestin and GFAP were quantified at 3d, 7d, 14d, 21d and 28d
post-ischemia. Results showed that NRIPostC significantly reduced acute
infarction and improved neurological outcomes during the recovery phase.
Meanwhile, NRIPostC significantly increased the number of BrdU+/nestin+ cells in SGZ on day 14 and in the SVZ on days 3, 7 and 14 respectively, and the number of DCX+ cells from days 3 to 14. There were significant increments in the number of BrdU+/NeuN+ and BrdU+/GFAP+
cells in the SGZ and SVZ during the stroke recovery. The changing
tendency of the protein expression of nestin and GFAP in DG was
consistent with the result mentioned above. In conclusion, NRIPostC
reduced acute infarction and improved functional outcomes up to 28d, and
it induced neurogenesis both in the SGZ and SVZ.